Prevalence of people at risk of developing type 2 diabetes mellitus and the involvement of community pharmacies in a national screening campaign: a pioneer action in Brazil.
Prevalence of people at risk of developing type 2 diabetes mellitus and the involvement of community pharmacies in a national screening campaign: a pioneer action in Brazil.
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DOI：
10.1186/s13098-020-00593-5
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发表时间：
2020
影响因子：
4.8
通讯作者：
João WSJ
中科院分区：
文献类型：
--
作者：
Correr CJ;Coura-Vital W;Frade JCQP;Nascimento RCRM;Nascimento LG;Pinheiro EB;Ferreira WM;Reis JS;Melo KFS;Pontarolo R;Lenzi MSA;Almeida JV;Pedrosa HC;João WSJ
巴西是糖尿病（DM）患者人数最多的10个国家之一，影响到1680万人。据估计，该国有770万人（20-79岁）尚未得到诊断，诊断不足率为46.0%。在此，我们的目的是通过巴西的社区药房筛查高血糖或2型糖尿病（T2 DM）风险的人群。2018年11月进行了一项横断面研究，涉及来自巴西345个城市的977名药剂师。这项研究评估了20至79岁之间的人，以前没有糖尿病的诊断。当空腹血糖值≥ 100 mg/dL且在随意进食状态下血糖值≥ 140 mg/dL时，认为血糖较高。FINDRISC（芬兰糖尿病风险评分）用于估计发生T2 DM的风险。高血糖的患病率进行估计，并获得相关因素，使用泊松多变量分析稳健方差。在全国筛查运动期间，有17 580人接受了检测，大多数咨询（78.2%）是在私人药店进行的。人口主要由妇女（59.5%）和20至45岁的人（47.9%）组成。高血糖受试者的频率为18.4%（95% CI 17.9-19.0）。考虑到FINDRISC，22.7%的人有高或非常高的T2 DM风险。与高血糖相关的危险因素为：体重指数> 25 kg/m2，男性腹围> 94 cm，女性> 80 cm;文化程度在15年以下，每日不摄入蔬菜水果;既往诊断为动脉高血压;有高血糖史和DM家族史。这是一项最大规模的筛查研究，评估了巴西社区药房中既往未诊断过高血糖的人群的高血糖频率及其相关因素。这些结果可能有助于改善公共卫生政策，并加强药剂师在针对巴西等大陆国家未确诊人群的筛查和教育行动中的作用。
Brazil is one of top 10 countries with the highest number of people with diabetes mellitus (DM), affecting 16.8 million peoples. It is estimated that 7.7 million people (20–79 years) in the country have not yet been diagnosed, representing an under-diagnosis rate of 46.0%. Herein we aimed to screen people for high blood glucose or risk for developing type 2 DM (T2DM) through community pharmacies in Brazil. A cross-sectional study was carried out in November 2018, involving 977 pharmacists from 345 municipalities in Brazil. The study evaluated people between 20 and 79 years old without a previous diagnosis of DM. Glycemia was considered high when its value was ≥ 100 mg/dL fasting and ≥ 140 mg/dL in a casual feeding state. The FINDRISC (Finnish Diabetes Risk Score) was used to estimate the risk for developing T2DM. The prevalence of high blood glucose was estimated and the associated factors were obtained using Poisson's multivariate analysis with robust variance. During the national screening campaign, 17,580 people were tested with the majority of the consultations (78.2%) being carried out in private pharmacies. The population was composed mainly of women (59.5%) and people aged between 20 and 45 years (47.9%). The frequency of participants with high blood glucose was 18.4% (95% CI 17.9–19.0). Considering the FINDRISC, 22.7% of people had a high or very high risk for T2DM. The risk factors associated with high blood glucose were: Body Mass Index > 25 kg/m2, abdominal circumference > 94 cm for men and > 80 cm for women; education level below 15 years of study, no daily intake of vegetables and fruits; previous diagnosis of arterial hypertension; history of high blood glucose and family history of DM. This is the largest screening study that evaluated the frequency of high blood glucose and its associated factors in a population without a previous diagnosis ever performed in community pharmacies in Brazil. These results may help to improve public health policies and reinforce the role of pharmacists in screening and education actions aimed at this undiagnosed population in a continent-size country such as Brazil.
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DOI：
10.1097/med.0000000000000320
发表时间：
2017-04
期刊：
Current opinion in endocrinology, diabetes, and obesity
影响因子：
--
作者：
Grisold A;Callaghan BC;Feldman EL
通讯作者：
Feldman EL
影响因子：
4.4
作者：
Dhippayom, Teerapon;Fuangchan, Anjana;Chaiyakunapruk, Nathorn
通讯作者：
Chaiyakunapruk, Nathorn
影响因子：
3.7
作者：
Arredondo A;Aviles R
通讯作者：
Aviles R
影响因子：
--
作者：
Hersberger, Kurt E.;Botomino, Andrea;Bruppacher, Rudolf
通讯作者：
Bruppacher, Rudolf
影响因子：
2.4
作者：
Correr, Cassyano Januario;Melchiors, Ana Carolina;Pontarolo, Roberto
通讯作者：
Pontarolo, Roberto