Association of sleep characteristics with cardiovascular health among women and differences by race/ethnicity and menopausal status: findings from the American Heart Association Go Red for Women Strategically Focused Research Network
Association of sleep characteristics with cardiovascular health among women and differences by race/ethnicity and menopausal status: findings from the American Heart Association Go Red for Women Strategically Focused Research Network
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DOI：
10.1016/j.sleh.2019.05.005
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发表时间：
2019-10-01
期刊：
影响因子：
4.1
通讯作者：
Aggarwal, Brooke
中科院分区：
文献类型：
--
作者：
Makarem, Nour;St-Onge, Marie-Pierre;Aggarwal, Brooke
背景和目的：睡眠是心血管疾病（CVD）的一个新兴危险因素，目前未被美国心脏协会的生活简单7 （AHA LS7）纳入心血管健康（CVH）指标。我们的目的是评估女性睡眠与CVH的关系，并检查绝经状态和种族/民族的差异。方法：对哥伦比亚大学AHA女性战略重点研究网络的基线数据进行检查。睡眠习惯是通过有效的问卷自我报告的。CVH评分采用AHA LS7标准，包括吸烟、饮食、体力活动、BMI、血压（BP）、总胆固醇和空腹血糖。根据满足AHA LS7指标的水平，女性获得2分（理想）、1分（中等）或0分（差）。使用多变量调整回归模型来评估睡眠与满足总体和个体CVH指标的关系。结果：分析样本包括n = 507名女性（62%为少数族裔/西班牙裔，平均年龄37岁）。睡眠时间充足（>= 7小时）、睡眠质量良好、无失眠、无打鼾、OSA风险低的参与者更有可能达到AHA LS7指标的>4 （P < 0.01）。较差的睡眠质量（beta = -0.08, P = .002）、较高的失眠严重程度（beta = -0.05, P = .002）、打鼾（beta = -0.77, P = .0001）和较高的OSA风险（beta = -1.63, P < .0001）与较差的CVH相关。失眠、打鼾和高OSA风险与CVH (P)差的几率增加69%至300%相关
Background and Objective: Sleep is an emerging risk factor for cardiovascular disease (CVD) that is not currently included as a cardiovascular health (CVH) metric in the American Heart Association's Life's Simple 7 (AHA LS7). Our objective was to evaluate the association of sleep with CVH in women and examine differences by menopausal status and race/ethnicity.Methods: Baseline data from the Columbia University AHA Go Red for Women Strategically Focused Research Network were examined. Sleep habits were self-reported using validated questionnaires. A CVH score was computed using AHA LS7 criteria for smoking, diet, physical activity, BMI, blood pressure(BP), total cholesterol, and fasting glucose. Women received a score of 2 (ideal), 1 (intermediate), or 0 (poor) based on their level of meeting each AHA LS7 metric. Multivariable-adjusted regression models were used to evaluate associations of sleep with meeting overall and individual CVH metrics.Results: The analytical sample consisted of n = 507 women (62% minority/Hispanic, mean age:37 y). Participants with adequate sleep duration (>= 7 h), good sleep quality, no insomnia nor snoring, and low risk for OSA were more likely to meet >4 of the AHA LS7 metrics (P < .01). Poorer sleep quality (beta = -0.08, P = .002), higher insomnia severity (beta = -0.05, P = .002), snoring (beta = -0.77, P = .0001), and higher risk for OSA (beta = -1.63, P < .0001) were associated with poorer CVH. Insomnia, snoring, and high OSA risk were associated with 69% to >300% higher odds of having poor CVH (P