Prevalence of obstructive sleep apnea syndrome in a cohort of 1,207 children of Southern Italy
Prevalence of obstructive sleep apnea syndrome in a cohort of 1,207 children of Southern Italy
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DOI：
10.1378/chest.120.6.1930
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发表时间：
2001-12-01
期刊：
影响因子：
9.6
通讯作者：
Armenio, L
中科院分区：
文献类型：
--
作者：
Brunetti, L;Rana, S;Armenio, L
研究目的：确定意大利南部学龄和学龄前儿童大队列中睡眠相关呼吸障碍的患病率。设计和设置：本横断面患病率研究设计为两个阶段：筛选阶段，旨在通过自填问卷从1，207名队列中识别有症状的儿童，和工具阶段，用于定义睡眠相关障碍。患者和方法：1207名儿童进行了筛选的自我管理的问卷调查。有612名女童（51%）和595名男童（平均年龄，7.3岁;范围，3至11岁）。根据回答，我们将儿童分为三组：不打鼾者、偶尔打鼾者和习惯性打鼾者。所有习惯性打鼾儿童均接受多导睡眠图家庭评估，氧饱和度下降指数> 2的儿童考虑进行夜间多导睡眠图监测（NPM）。结果：共回收问卷895份（74.2%），其中无打鼾者710名（79.3%），偶尔打鼾者141名（15.8%），习惯性打鼾者44名（4.9%）。习惯性打鼾的男孩的百分比高于习惯性打鼾的女孩的百分比（分别为6.1%和3.7%; p < 0.09）。结论：儿童OSAS患病率下限为1%（95%可信区间为0.8 ~ 1.2）。如果我们加上5名因临床状况恶化而接受腺样体切除术和/或扁桃体切除术的儿童，以及2名经呼吸道血氧测定显示有OSAS证据的儿童，则患病率为1.8%（患病率上限; 95%CI，1.6 - 2.0）。
Study objective: To determine the prevalence of sleep-related breathing disturbances in a large cohort of school-aged and preschool-aged children of Southern Italy.Design and setting: This cross-sectional prevalence study was designed in two phases: a screening phase aimed to identify symptomatic children from a cohort of 1,207 by a self-administered questionnaire, and an instrumental phase for the definition of sleep-related disorders.Patients and methods: One thousand two hundred seven children were screened by a self-administered questionnaire. There were 612 female children (51%) and 595 male children (mean age, 7.3 years; range, 3 to 11 years). According to answers, children we re classified in three groups: nonsnorers, occasional snorers, and habitual snorers. All habitual snoring children underwent a polysomnographic home evaluation, and those with an oxygen desaturation index > 2 were considered for nocturnal polygraphic monitoring (NPM). Children with an apnea/ hypopnea index > 3 received a diagnosis of obstructive sleep apnea syndrome (OSAS).Results: A total of 895 questionnaires (74.2%) were returned and scored; 710 children (79.3%) were identified as nonsnorers, 141 children (15.8%) were identified as occasional snorers, and 44 children (4.9%) were identified as habitual snorers. The percentage of male children who were habitual snorers was higher than the percentage of female children who were habitual snorers (6.1% vs 3.7%, respectively; p < 0.09). OSAS was diagnosed in nine children by NPM.Conclusion: The lower limit of prevalence of OSAS in childhood is 1% (95% confidence interval [CI], 0.8 to 1.2). If we add the five children who underwent adenoidectomy and/or tonsillectomy because of worsening clinical condition and the two children who were shown to have evidence of OSAS on domiciliary oximetry, then the prevalence is 1.8% (higher limit of prevalence; 95% CI, 1.6 to 2.0).