Genome-Wide SNP Analysis Reveals Population Structure and Demographic History of the Ryukyu Islanders in the Southern Part of the Japanese Archipelago
Genome-Wide SNP Analysis Reveals Population Structure and Demographic History of the Ryukyu Islanders in the Southern Part of the Japanese Archipelago
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DOI：
10.1093/molbev/msu230
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发表时间：
2014-11-01
影响因子：
10.7
通讯作者：
Oota, Hiroki
中科院分区：
文献类型：
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作者：
Sato, Takehiro;Nakagome, Shigeki;Oota, Hiroki
琉球群岛位于日本群岛的西南部。考古证据表明，在琉球北部的奄美岛和冲绳岛与琉球南部的宫古岛和八山岛之间存在史前文化差异。为了研究琉球群岛的遗传细分，我们对冲绳群岛、宫古群岛和八山群岛的居民进行了全基因组单核苷酸多态性分型。主成分分析和聚类分析表明，冲绳和宫古岛之间存在遗传差异。没有观察到台湾原住民与琉球族群之间的遗传亲缘关系。冲绳岛和宫古岛居民之间的遗传差异很可能是由于遗传漂变而不是与邻近地区的人混合而产生的。根据观察到的遗传差异，冲绳岛和宫古岛居民的分化时间可以追溯到全新世。这些发现表明，在琉球群岛南部发现的更新世居民，如果有的话，对琉球群岛南部今天的居民没有重大的遗传贡献。
The Ryukyu Islands are located to the southwest of the Japanese archipelago. Archaeological evidence has revealed the existence of prehistoric cultural differentiation between the northern Ryukyu islands of Amami and Okinawa, and the southern Ryukyu islands of Miyako and Yaeyama. To examine a genetic subdivision in the Ryukyu Islands, we conducted genome-wide single nucleotide polymorphism typing of inhabitants from the Okinawa Islands, the Miyako Islands, and the Yaeyama Islands. Principal component and cluster analyses revealed genetic differentiation among the island groups, especially between Okinawa and Miyako. No genetic affinity was observed between aboriginal Taiwanese and any of the Ryukyu populations. The genetic differentiation observed between the inhabitants of the Okinawa Islands and the Miyako Islands is likely to have arisen due to genetic drift rather than admixture with people from neighboring regions. Based on the observed genetic differences, the divergence time between the inhabitants of Okinawa and Miyako islands was dated to the Holocene. These findings suggest that the Pleistocene inhabitants, whose bones have been found on the southern Ryukyu Islands, did not make a major genetic contribution, if any, to the present-day inhabitants of the southern Ryukyu Islands.