Neural mechanisms of impulse control in sexually risky adolescents
Neural mechanisms of impulse control in sexually risky adolescents
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DOI：
10.1016/j.dcn.2013.06.002
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发表时间：
2013-10-01
影响因子：
4.7
通讯作者：
Galvan, Adriana
中科院分区：
文献类型：
--
作者：
Goldenberg, Diane;Telzer, Eva H.;Galvan, Adriana
危险性行为的后果引起了公众的关注。青少年对危险性行为的负面后果造成了不成比例的影响。然而，还没有研究检查这一人群中冲动控制和现实世界参与危险性行为的神经相关性。本研究的目的就是探讨这一问题。20名性行为活跃的青少年在功能性磁共振成像(FMRI)扫描期间进行了冲动控制任务，并通过自我报告评估了危险的性行为。性风险等级与反应抑制期间前额叶皮质的激活呈负相关。这些结果表明，冲动控制回路的参与减少可能会导致青少年的性风险。爱思唯尔有限公司出版。
The consequences of risky sexual behavior are of public concern. Adolescents contribute disproportionately to negative consequences of risky sexual behavior. However, no research has examined the neural correlates of impulse control and real-world engagement in risky sexual behavior in this population. The aim of the present study was to examine this question. Twenty sexually active adolescents performed an impulse control task during a functional magnetic resonance imaging (fMRI) scan and risky sexual behaviors were assessed through self-report. Sexual riskiness ratings were negatively associated with activation in the prefrontal cortex during response inhibition. These results suggest that diminished engagement of impulse control circuitry may contribute to sexual riskiness in adolescents. Published by Elsevier Ltd.