SITE DIFFERENCES IN THE BASAL-METABOLISM OF SUBCUTANEOUS FAT IN OBESE WOMEN
SITE DIFFERENCES IN THE BASAL-METABOLISM OF SUBCUTANEOUS FAT IN OBESE WOMEN
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DOI：
10.1210/jcem-53-5-948
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发表时间：
1981-01-01
影响因子：
5.8
通讯作者：
LITHELL, H
中科院分区：
文献类型：
--
作者：
ARNER, P;ENGFELDT, P;LITHELL, H
在禁食前和禁食1周期间，研究了肥胖妇女股骨和腹部脂肪水解和储存酰基甘油的基础能力。禁食前，股脂肪的脂解活性低于腹脂肪，脂蛋白脂酶活性高于腹脂肪。在禁食期间，股脂肪脂蛋白脂肪酶活性降低，脂解活性增加到与腹部脂肪相似的水平。酰甘油合成在禁食前的2个脂肪库中相似，但在禁食期间，腹部的酰甘油合成水平低于股骨部位。在禁食期间，腹部脂肪细胞大小减少，但股部脂肪细胞大小没有减少。因此，在进食和禁食状态下均发现脂肪储存和动员的区域差异。
The basal capacity of femoral and abdominal fat to hydrolyze and store acylglycerols was investigated in obese women before and during 1 wk of fasting. Before fasting, the lipolytic activity was lower and the lipoprotein lipase activity higher in femoral than in abdominal fat. During fasting, femoral fat lipoprotein lipase activity decreased and lipolytic activity increased to levels similar to those in abdominal fat. Acylglycerol syntheses were similar in the 2 fat depots before fasting, but decreased to a lower level at the abdominal than at the femoral site during fasting. Fat cell size decreased in the abdominal but not in the femoral site during fasting. Thus, regional variations in storage and mobilization of fat were found both in the fed and fasted states.