Aesthetic and functional results after breast conserving surgery as correlates of quality of life measured by a German version of the Breast Cancer Treatment Outcome Scale (BCTOS)

Aesthetic and functional results after breast conserving surgery as correlates of quality of life measured by a German version of the Breast Cancer Treatment Outcome Scale (BCTOS)
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DOI:
10.1016/j.breast.2010.05.004
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发表时间:
2010-12-01
期刊:
影响因子:
3.9
通讯作者:
Sohn, Christof
Sohn, Christof
中科院分区:
医学2区
文献类型:
--
作者:
Heil, Joerg;Holl, Simone;Sohn, Christof

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本前瞻性队列研究旨在开发德国版的乳腺癌治疗结果量表(BCTOS),并探讨保乳手术后美学和功能结果与生活质量(QoL)的关系。因素分析显示德国BCTOS有3个内部一致的量表:美学状态、功能状态和乳房敏感状态,QoL采用EORTC生活质量问卷C30-BR 23(EORTC)测量。所有BCTOS量表与EORTC量表相关。相关幅度范围为0.24至0.67(p < 0.001)。多元回归分析证实了这些结果。相关协变量的分析表明,年轻患者在所有BCTOS量表上的状态较差。美学和功能结果似乎与生活质量密切相关。德国的BCTOS证明是一个有用的工具。(C)2010爱思唯尔有限公司保留所有权利。
This prospective cohort study was carried out to develop a German version of the Breast Cancer Treatment Outcome Scale (BCTOS) and to examine the relations of aesthetic and functional outcome after breast conserving surgery with quality of life (QoL).The study included 189 patients with one-sided, early stage breast cancer. A factor analysis indicated three internally consistent scales of the German BCTOS: Aesthetic Status, Functional Status and Breast Sensitivity Status.QoL was measured by the EORTC Quality of Life Questionnaire C30-BR23 (EORTC). All BCTOS scales were correlated with scales of the EORTC. Correlation magnitudes ranged from 0.24 to 0.67 (p < 0.001). A multiple regression analyses confirmed these results. The analysis of relevant covariates demonstrated that younger patients revealed poorer status on all BCTOS scales.Aesthetic and functional outcome seems to be closely related to quality of Life. The German BCTOS demonstrated to be a useful instrument. (C) 2010 Elsevier Ltd. All rights reserved.