Effects of non-equilibrium plasma in the treatment of ligature-induced peri-implantitis

Effects of non-equilibrium plasma in the treatment of ligature-induced peri-implantitis
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非平衡血浆治疗结扎引起的种植体周围炎的效果

DOI:
10.1111/jcpe.12403
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发表时间:
2015-05-01
影响因子:
6.7
通讯作者:
Cao, Yingguang
Cao, Yingguang
中科院分区:
医学1区
文献类型:
--
作者:
Shi, Qi;Song, Ke;Cao, Yingguang

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目的评价非平衡血浆治疗Beagle犬结扎引起的种植体周围炎的效果。材料与方法6只Beagle犬在下颌第四前磨牙位置植入12颗种植体。结扎诱导的种植体周围炎在种植后 3 个月开始。当大约 40% 的支撑骨丢失时,结扎线被移除。对植入物进行粘膜骨膜刮治和氯己定冲洗,有或没有等离子冲洗。三个月后,进行了临床、放射学和微生物学分析。准备块活检用于显微 CT 和组织形态学分析。主要结果是种植体周围部位骨愈合的差异,次要结果包括临床参数(SBI、PD)和细菌检测的变化。结果在基线时,两组之间没有观察到显着差异。治疗后 3 个月,血浆组的骨水平显着高于对照组(p
AimTo evaluate the effects of non-equilibrium plasma in the treatment of ligature-induced peri-implantitis in beagle dogs.Materials and MethodsSix beagles received 12 implants installed in the position of the fourth mandibular premolars. Ligature-induced peri-implantitis was initiated at 3months post-implantation. When approximately 40% of the supporting bone was lost, the ligatures were removed. The implants were subjected to the muco-periosteal scaling and chlorhexidine irrigation with or without plasma irrigation. Three months later, clinical, radiographic and microbiological analyses were performed. Block biopsies were prepared for micro-CT and histomorphometric analysis. The primary outcome was the difference in bone healing of peri-implant sites, and the secondary outcomes included changes in clinical parameters (SBI, PD) and bacterial detection.ResultsAt baseline, no significant differences were observed between the two groups. At 3months post-treatment, the plasma group showed a significantly higher bone level than the control group (p