Heteroplasmy in a deep-sea protobranch bivalve suggests an ancient origin of doubly uniparental inheritance of mitochondria in Bivalvia
Heteroplasmy in a deep-sea protobranch bivalve suggests an ancient origin of doubly uniparental inheritance of mitochondria in Bivalvia
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DOI：
10.1007/s00227-012-2099-y
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发表时间：
2013-02-01
期刊：
影响因子：
2.4
通讯作者：
Etter, Ron J.
中科院分区：
文献类型：
--
作者：
Boyle, Elizabeth E.;Etter, Ron J.
大多数后生动物物种的线粒体基因组具有严格的母系遗传。在双壳类中，一种独特的遗传模式称为双单亲遗传（DUI），至少发生在7个双壳类家族中。在这个线粒体遗传系统中，男性继承并携带来自父母双方的mtDNA，而女性只携带来自母亲的mtDNA。在这里，我们提出的证据线粒体异质性在深海原鳃双壳类。不同的16 S rRNA和细胞色素B序列内获得的个体Ledella ultima。Ledella sublevis也表现出不同的16S序列。每个物种的16S序列在个体内的差异水平分别为27%和15%。同质异质个体的比例没有显着差异，从1：1，在协议与性别比例在原鳃。结果提供了第一个证据线粒体异质性的原鳃类，并建议DUI可能已经进化得更早的双壳类的进化比以前认为的。
Most metazoan species have strict maternal inheritance of the mitochondrial genome. In bivalves, a unique inheritance pattern called doubly uniparental inheritance (DUI) occurs in at least seven bivalve families. In this system of mitochondrial inheritance, males inherit and carry mtDNA from both parents, while females only carry mtDNA from the mother. Here, we present evidence of mitochondrial heteroplasmy in deep-sea protobranch bivalves. Divergent 16S rRNA and cytochrome b sequences were obtained within individuals of Ledella ultima. Ledella sublevis also exhibited divergent 16S sequences. Levels of divergence between 16S sequences within individuals were 27 and 15 % for each species, respectively. Ratios of homoplasmic to heteroplasmic individuals were not significantly different from 1:1, in agreement with sex ratios in protobranchs. The results provide the first evidence for mitochondrial heteroplasmy in the protobranchs and suggest DUI might have evolved much earlier in the evolution of the Bivalvia than previously thought.