Primary tumors of the brain, cranial nerves and cranial meninges in Victoria, Australia, 1982-1990: patterns of incidence and survival.
Primary tumors of the brain, cranial nerves and cranial meninges in Victoria, Australia, 1982-1990: patterns of incidence and survival.
复制标题
澳大利亚维多利亚州 1982-1990 年脑、颅神经和脑膜的原发性肿瘤：发病率和生存模式。
DOI：
10.1159/000110328
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发表时间：
1993
影响因子：
5.7
通讯作者：
Giles,G
中科院分区：
文献类型：
--
作者：
Preston-Martin,S;Staples,M;Farrugia,H;Giles,G
本报告首次详细分析了澳大利亚人群中原发性脑肿瘤的分布情况。利用1982年至1990年在维多利亚州居民中诊断出的3 575例良性和恶性脑、脑神经和脑膜肿瘤的数据，按组织学类型、年龄和性别计算发病率和生存率，并按出生地、社会经济地位和诊断年份比较发病率。60岁以上人群的发病率未见急剧下降，在9年期间仅观察到发病率的小幅增加。在南欧、东欧和中东出生的人群中，总体发病率、按组织学类型划分的分布以及发病率过高的模式与其他地理区域的观察结果相似。发病率与社会经济地位之间没有明显的关系。女性在脑肿瘤诊断后的生存率高于男性（52% vs. 37%）；这种差异可归因于男性患恶性肿瘤的频率更高。最显著的男性多于女性是髓母细胞瘤，这种类型主要发生在儿科年龄组。这种过度的现象，加上这种肿瘤发生在男性中更年轻的事实，可能表明一些患有这种疾病的患者存在遗传易感性。
This report presents for the first time a detailed analysis of the distribution of primary brain tumors in a population in Australia. Data on 3,575 cases of benign and malignant tumors of the brain, cranial nerves and cranial meninges diagnosed among residents of the state of Victoria from 1982 to 1990 are used to calculate incidence rates and survival by histologic type, age and sex and to compare incidence by birthplace, socioeconomic status and year of diagnosis. No sharp decline in incidence rates is seen among those over age 60 and only small increases in incidence over the 9-year period have been observed. The overall incidence rates, distributions by histologic type, and patterns of excess incidence among those born in Southern and Eastern Europe and the Middle East are similar to observations in other geographic areas. No clear trend relating incidence and socioeconomic status is observed. Survival after brain tumor diagnosis is better among women then men (52 vs. 37% survive 5 years); this difference is attributable to the greater frequency among men of the more aggressive tumor types. The most striking male over female excess is for medulloblastoma, a type that occurs predominantly in the pediatric age group. This excess coupled with the fact that this tumor occurs at a much younger age in males may suggest the presence of a genetic predisposition in some patients with this disease.