Measurement of the oxygenation status of the isolated perfused rat heart using near infrared detection.

Measurement of the oxygenation status of the isolated perfused rat heart using near infrared detection.
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使用近红外检测测量离体灌注大鼠心脏的氧合状态。

DOI:
10.1007/978-1-4613-0333-6_18
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发表时间:
1996
影响因子:
--
通讯作者:
Chance,B
Chance,B
中科院分区:
医学4区
文献类型:
--
作者:
vanBeek,JH;Osbakken,MD;Chance,B

文献摘要

被引文献

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离体心脏的氧合状态通常使用光谱可见范围的光学检测方法来测量(Tamura等人,1989年)。据我们所知,还没有关于使用光谱的近红外区域中的检测方法测量肌红蛋白氧合的报道。另一方面,用于对组织进行近红外测量的设备广泛可用,并且在某些情况下相当便宜。因此,我们在本研究中调查是否在两个波长的近红外(NIR)检测提供了一种方便地确定肌红蛋白氧合在一个孤立的器官小盐水灌注大鼠心脏。
The oxygenation status of isolated hearts has often been measured using optical detection methods for the visible range of the spectrum (Tamura et al., 1989). To the best of our knowledge there are no reports on measurement of myoglobin oxygenation using detection methods in the near-infrared region of the spectrum. On the other hand, equipment for near-infrared measurements on tissue is widely available and is in some instances quite inexpensive. Therefore we investigated in the present study whether near-infrared (NIR) detection at two wavelengths provides a way to conveniently determine myoglobin oxygenation in an isolated organ as small as the saline-perfused rat heart.