Differentiation of respiratory and abortigenic isolates of equine herpesvirus 1 by restriction endonucleases.
Differentiation of respiratory and abortigenic isolates of equine herpesvirus 1 by restriction endonucleases.
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通过限制性核酸内切酶区分马疱疹病毒 1 的呼吸道和致流产分离株。
DOI：
10.1126/science.6270790
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Roizman,B
中科院分区：
文献类型：
--
作者：
Studdert,MJ;Simpson,T;Roizman,B
被免疫学标准归类为马疱疹病毒1型的病毒会引起马匹的呼吸道疾病和流产。对患有呼吸道疾病的动物和流产胎儿的病毒DNA的限制性内切酶分析表明，呼吸道病毒的模式虽然彼此相似，但与胎儿病毒的模式完全不同。因此，建议将本研究中分析的胎儿病毒和呼吸道病毒的DNA限制性内切酶图谱分别命名为马疱疹病毒1型和4型的原型。
Viruses classified by immunologic criteria as equine herpesvirus 1 cause respiratory disease and abortion in horses. Restriction endonuclease analyses of the DNA's of viruses from animals with respiratory disease and from aborted fetuses show that the patterns for respiratory viruses, while similar to each other, are entirely different from the patterns for fetal viruses. It is therefore proposed that the DNA restriction endonuclease patterns of fetal and respiratory viruses analyzed in this study be designated as prototypic of equine herpesvirus 1 and 4, respectively.