Ensemble machine learning for the prediction of patient-level outcomes following thyroidectomy.
Ensemble machine learning for the prediction of patient-level outcomes following thyroidectomy.
复制标题
甲状腺切除术后患者水平结局的预测的集合机器学习。
DOI:
10.1016/j.amjsurg.2020.11.055
复制
发表时间:
2021-08
影响因子:
3
通讯作者:
Suh I
中科院分区:
文献类型:
--
作者:
Seib CD;Roose JP;Hubbard AE;Suh I
Accurate prediction of thyroidectomy complications is necessary to inform treatment decisions. Ensemble machine learning provides one approach to improve prediction. We applied the Super Learner (SL) algorithm to the 2016–2018 thyroidectomy-specific NSQIP database to predict complications following thyroidectomy. Cross-validation was used to assess model discrimination and precision. For the 17,987 patients undergoing thyroidectomy, rates of recurrent laryngeal nerve injury, post-operative hypocalcemia prior to discharge or within 30 days, and neck hematoma were 6.1%, 6.4%, 9.0%, and 1.8%, respectively. SL improved prediction of thyroidectomy-specific outcomes when compared with benchmark logistic regression approaches. For postoperative hypocalcemia prior to discharge, SL improved the cross-validated AUROC to 0.72 (95%CI 0.70–0.74) compared to 0.70 (95%CI 0.68–0.72; p<0.001) when using a manually curated logistic regression algorithm. Ensemble machine learning modestly improves prediction for thyroidectomy-specific outcomes. SL holds promise to provide more accurate patient-level risk prediction to inform treatment decisions.
登录
查看更多内容
影响因子:
2
作者:
Kosinski, Andrzej S.
通讯作者:
Kosinski, Andrzej S.
影响因子:
3.8
作者:
Iannuzzi, James C.;Fleming, Fergal J.;Moalem, Jacob
通讯作者:
Moalem, Jacob
影响因子:
1.6
作者:
Caulley, Lisa;Johnson-Obaseki, Stephanie;Javidnia, Hedyeh
通讯作者:
Javidnia, Hedyeh
DOI:
10.1198/106186006x133933
发表时间:
2006-09-01
影响因子:
2.4
作者:
Hothorn, Torsten;Hornik, Kurt;Zeileis, Achim
通讯作者:
Zeileis, Achim
影响因子:
2.5
作者:
HOERL, AE;KENNARD, RW
通讯作者:
KENNARD, RW