Aspergillus: 50 years on.
Aspergillus: 50 years on.
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发表时间：
1994
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通讯作者：
J. R. Kinghorn
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作者：
J. R. Kinghorn
作为英国为数不多的没有本书一章的曲霉菌工作者之一（毫无疑问为什么我被要求审阅它！），我有一个独特的机会来冒犯或讨好我的大部分同事和同事。因此，我感到有些欣慰的是，我能够祝贺编辑们成功完成了一项艰巨的任务。这本书汇集了许多杰出的作者，庆祝使用构巢曲霉作为实验生物进行研究 50 周年。这本书的篇幅（880 页）反映了该领域自 20 世纪 40 年代格拉斯哥大学起步以来所进行的大量研究。这是一份及时的出版物，在人们对曲霉属物种越来越感兴趣的时期出版，曲霉属物种既可以作为实验室的模型系统，也可以作为生物技术行业的工具。本书以构巢构巢菌遗传学公认奠基人 Guido Pontecorvo 的序言开头，然后进入介绍性部分，旨在让读者熟悉这种生物体和作者。尽管后者近乎自我放纵，但对于该领域的新手来说，这是一个有趣的叙述，生动地传达了曲霉菌研究早期格拉斯哥实验室的气氛。本书的其余部分又分为七个部分，总共 28 章和四个附录。涵盖的主题包括新陈代谢、基因调控、细胞周期和发育、分子工具、应用方面以及包含介质详细信息、基因命名等的有用的最后部分。总体呈现水平较高。大多数章节都写得清晰简明，具有高质量的图形和摄影图像以及广泛的参考列表。像这样的书的成功程度不仅取决于个人贡献的质量，还取决于贡献者的选择及其专业。总的来说，这个选择是平衡的，公平地反映了曲霉属研究的现状。这本书无疑是该主题的综合性论文，包含丰富的核心信息。它不可避免地存在此类书籍的典型缺陷。也就是说，它的酝酿时间太长了，最近的参考文献是 1993 年。事实上，至少其中一章已同时在其他地方出版（以修改的形式）！尽管这并不影响本书的一般实用性，但忠实的读者必须查阅更新的论文才能完全了解当前的知识。这是一本巨著，价格也相当合理（210）。不幸的是，在经济紧张的时期，高昂的价格将使这本书远远超出研究生的承受能力（他们会发现它是无价的），并且可能会增加高等教育机构大多数研究人员的预算。
As one of the few Aspergillus workers in the UK without a chapter in this book (doubtless why I was asked to review it!), I am presented with a unique opportunity for either offending or endearing myself to a large proportion of my co-workers and associates. Therefore, it is with some relief that I feel able to congratulate the editors on successfully completing a mammoth task. The book brings together a host of distinguished authors in a celebration of 50 years of research using Aspergillus nidulans as an experimental organism. The sheer size of the book (880 pages) reflects the volume of research that has been undertaken in this field since its humble beginnings at the University of Glasgow in the I 940s. It is a timely publication, arriving during a period of increasing interest in Aspergillus species, both as model systems in the laboratory and as tools for the biotechnology industry. Fittingly, the book opens with a foreword by the recognized founding father of A. nidulans genetics, Guido Pontecorvo, and then proceeds into an introductory section which aims to acquaint the reader with both the organism and authors. Although the latter borders on selfindulgence, it was, for a relative newcomer to the field, an amusing account which conveys vividly the atmosphere in the Glasgow laboratories during the early days of Aspergillus research. The remainder of the book is divided into a further seven sections, with a total of 28 chapters and four appendices. Topics covered include metabolism, gene regulation, cell cycle and development, molecular tools, applied aspects and a useful final section containing details of media, gene designations etcetera. The general level of presentation is high. Most of the chapters are clearly and concisely written, with goodquality graphical and photographic images and an extensive reference list. The degree of success of a book like this depends not only upon the quality of the individual contributions, but also upon the choice of contributors and their specialities. On the whole, the choice is wellbalanced and is a fair reflection of the current state of play inAspergillus research. The book is certainly a comprehensive treatise of the subject and contains a wealth of core information. Inevitably, it suffers from a defect typical of books of this nature; namely, it has been rather too long in gestation, the most recent references being 1993. Indeed, at least one of the chapters has been published elsewhere (in modified form) in the meantime! Although this does not detract from the general usefulness of the book, the committed reader would have to consult more recent papers in order to be entirely abreast with the current knowledge. This is a mighty tome with a price to match (210). In these times of economic constraint, it is unfortunate that the high price will put the book well beyond the reach of postgraduate students (who would find it invaluable) and will probably stretch the budgets of most researchers in HE institutes.