Neural systems underlying the recognition of familiar and newly learned faces
Neural systems underlying the recognition of familiar and newly learned faces
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DOI：
10.1523/jneurosci.20-02-00878.2000
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发表时间：
2000-01-15
影响因子：
5.3
通讯作者：
Rao, SM
中科院分区：
文献类型：
--
作者：
Leveroni, CL;Seidenberg, M;Rao, SM
对名人面孔的记忆可以用来研究从长期记忆中提取的神经系统。迄今为止，对著名人脸识别的功能性神经成像研究数量有限。在这项研究中，我们比较了对著名面孔的识别和对新面孔的识别。采用全脑事件相关功能磁共振成像技术，对11名被试在对陌生面孔进行编码和熟悉度判断时的神经活动区域变化进行了成像，分别为：(1)新面孔、(2)不熟悉面孔干扰物和(3)知名面孔。图像分析仅限于正确识别试验。对著名面孔和最近学过的面孔的识别准确率和反应时间相当。与对最近编码过的面孔或第一次看到的陌生面孔的识别相比，对著名面孔的识别与广泛的双侧大脑激活网络有关，涉及前额叶、外侧颞叶和内侧颞叶（海马区和海马旁区）区域。研究结果讨论了目前有关参与长期记忆检索的神经区域的建议，更具体地说，涉及从人身份语义系统中检索信息。
Memory for famous faces can be used to examine the neural systems underlying retrieval from long-term memory. To date, there have been a limited number of functional neuroimaging investigations examining famous face recognition. In this study, we compared recognition of famous faces to recognition of newly learned faces. Whole-brain, event-related functional magnetic resonance imaging was used to image regional changes in neural activity in 11 subjects during the encoding of unfamiliar faces and during familiarity judgments for: (1) newly learned faces, (2) unfamiliar face distractors, and (3) famous faces. Image analyses were restricted to correct recognition trials. Recognition accuracy and response time to famous and recently learned faces were equivalent. Recognition of famous faces was associated with a widespread network of bilateral brain activations involving the prefrontal, lateral temporal, and mesial temporal (hippocampal and parahippocampal regions) regions compared to recognition of recently encoded faces or unfamiliar faces seen for the first time. Findings are discussed in relation to current proposals concerning the neural regions thought to participate in long-term memory retrieval and, more specifically, in relation to retrieval of information from the person identity semantic system.