[Sepsis and acute kidney injury].
[Sepsis and acute kidney injury].
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DOI：
10.3760/cma.j.cn112137-20201201-03232
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发表时间：
2021-05-11
影响因子：
--
通讯作者：
Peng, Z Y
中科院分区：
文献类型：
--
作者：
Li, Y M;Zhu, Y;Peng, Z Y
脓毒症是由感染引起的危及生命的多器官功能障碍综合征，肾脏是脓毒症最易损伤的器官之一。重症脓毒症患者常发生不同程度的急性肾损伤（阿基），死亡率高。脓毒症急性肾损伤的早期识别、发病机制、诊断和治疗等方面的研究越来越多。本文就急性肾损伤的早期诊断、病理生理机制、治疗、预后及随访等方面作一综述，以提高对急性肾损伤的认识，降低病死率。
Sepsis is a life-threatening multiple organ dysfunction syndrome caused by infection, and kidney is one of the most organs susceptible to injury in sepsis. Critical ill patients with sepsis often suffer from acute kidney injury (AKI) of varying degrees with a high mortality. There are more and more researches on the early identification, pathogenesis, diagnosis and treatment of acute kidney injury in sepsis. In order to improve the understanding and reduce the mortality of acute kidney injury, this review briefly discussed the early identification, physio-pathologic mechanism, treatment, prognosis and follow up.