Evaluation of endothelial function using finger plethysmography
Evaluation of endothelial function using finger plethysmography
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DOI：
10.1111/j.1475-097x.2009.00882.x
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发表时间：
2009-09-01
影响因子：
1.8
通讯作者：
Agewall, S.
中科院分区：
文献类型：
--
作者：
Faizi, A. K.;Kornmo, D. W.;Agewall, S.
背景：本研究的目的是建立血流阻断的最佳持续时间以获得最大反应，并比较下臂和上臂阻断后的反应。方法：使用新型手指体积描记器（EndoPat; Itamar）分析脉搏波振幅。为测定前臂袖带阻塞引起的反应性充血指数（RHI），30名健康受试者在不同的时间以随机顺序进行四个袖带阻塞时间（1个中心点，5，3，5和8 min）的检查。结果：1个中心点、5分钟和3分钟前臂咬合引起的平均RHI低于8分钟前臂咬合引起的平均RHI（P = 0中心点002和P = 0中心点024）。5 min和8 min前臂咬合之间以及5 min前臂和5 min上臂咬合之间的值无显著差异（P = 0，中心点1）。所有受试者报告前臂闭塞后的不适感较少，与上臂occlusion.Conclusion：血流闭塞5分钟后达到最大反应，因此建议闭塞时间。前臂和上臂咬合后的反应没有显着差异。前臂闭塞可能是首选，因为这会导致更少的不适。
P>Background:The aims of this study were to establish the optimum duration of blood flow occlusion to obtain maximal response and to compare the response after lower-arm and upper-arm occlusion.Methods:Pulse wave amplitude was analysed using a novel finger plethysmograph (EndoPat; Itamar). For measuring reactive hyperaemic index (RHI) induced by forearm cuff occlusion, 30 healthy subjects were examined at different days in a random order of four cuff occlusion times (1 center dot 5, 3, 5 and 8 min). RHI induced by 5 min upper-arm cuff occlusion was also measured in 20 subjects.Results:Average RHI was lower with 1 center dot 5 and 3 min forearm occlusion compared with 8 min forearm occlusion (P = 0 center dot 002 and P = 0 center dot 024). There was no significant difference between values of 5 min and 8 min forearm occlusion and between 5 min forearm and 5 min upper-arm occlusion (P = 0 center dot 1). All subjects reported less discomfort after forearm occlusion compared with upper-arm occlusion.Conclusion:Maximum response was reached after 5 min of blood flow occlusion and therefore this occlusion time is recommended. The response after forearm and upper-arm occlusion did not differ significantly. Forearm occlusion might be preferred as this caused less discomfort.