Myosin heavy chain isoform changes in rat diaphragm are induced by endurance training.
Myosin heavy chain isoform changes in rat diaphragm are induced by endurance training.
复制标题
耐力训练可引起大鼠膈肌肌球蛋白重链亚型的变化。
DOI：
10.2170/jjphysiol.40.759
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
N. Murakami
中科院分区：
文献类型：
--
作者：
T. Sugiura;A. Morimoto;Y. Sakata;T. Watanabe;N. Murakami
大鼠通过耐力游泳进行长期锻炼后，观察到膈肌和 EDL 肌肉中的琥珀酸脱氢酶 (SDH) 活性增强。此外，耐力训练导致膈肌中肌球蛋白重链（MHC）IIb的百分比下降，并且伴随着EDL肌肉中HCIId百分比的增加，HCIIb百分比下降。这些结果表明，耐力训练不仅诱导氧化能力的增加，而且还导致膈肌和骨骼肌中 MHC 表型表达的改变。
After rats were chronically exercised by endurance swimming, an augmentation of succinic dehydrogenase (SDH) activity in the diaphragm and the EDL muscle was observed. In addition, endurance training induced a decrease in the percentage of myosin heavy chain (MHC) IIb in the diaphragm, and a decrease in the percentage of HCIIb concomitant with an increase in the percentage of HCIId in the EDL muscle. These results indicate that endurance training induced not only an increase of the oxidative capacity but also an alteration in the expression of an MHC phenotype in the diaphragm and skeletal muscle.