Aseptic Meningitis with Relapsing Polychondritis Mimicking Bacterial Meningitis
Aseptic Meningitis with Relapsing Polychondritis Mimicking Bacterial Meningitis
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DOI：
10.2169/internalmedicine.48.2173
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发表时间：
2009-01-01
影响因子：
1.2
通讯作者：
Sasaki, Hidenao
中科院分区：
文献类型：
--
作者：
Yaguchi, Hiroaki;Tsuzaka, Kazufumi;Sasaki, Hidenao
复发性多软骨炎（RP）是一种罕见的多系统自身免疫性疾病。虽然脑膜炎在RP不常见，一些病例与脑脊液（CSF）多细胞性淋巴细胞已被报道。在先前报道的18例病例中，2例在脑脊液中表现出多形核白细胞（PMN）。此外，脑脊液中葡萄糖水平降低的病例也被观察到。我们的病例也表现出脑脊液中PMN的增多，类似细菌性脑膜炎。在临床领域，由于不可能在入院当天获得脑脊液培养，葡萄糖水平和细胞分数被认为是重要的。因此，RP的脑膜炎应被视为细菌性脑膜炎的鉴别诊断。
Relapsing polychondritis (RP) is a rare multisystem autoimmune disease. Though meningitis in RP is not common, some cases with cerebrospinal fluid (CSF) pleocytosis of the lymphocyte cells have been reported. Of the 18 previously reported cases, two cases demonstrated pleocytosis of polymorphonuclear leukocytes (PMN) in the CSF. In addition, cases with a decreased glucose level in the CSF were also seen. Our case also demonstrated pleocytosis of PMN in CSF mimicking bacterial meningitis. In the clinical field, as it is not possible to obtain a culture of CSF on admission day, the glucose level and cellular fraction are considered important. Therefore, meningitis in RP should be considered as a differential diagnosis of bacterial meningitis.