High-sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers
High-sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers
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DOI：
10.1364/ol.27.001168
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发表时间：
2002-07-01
期刊：
影响因子：
3.6
通讯作者：
Ye, J
中科院分区：
文献类型：
--
作者：
Potma, EO;Jones, DJ;Ye, J
我们证明了一个显着的改善，在相干反斯托克斯拉曼散射（汽车）光谱/显微镜的信噪比，使用两个高度同步的皮秒钛：蓝宝石激光器。两个独立的商业激光器的脉冲序列之间的时间抖动从几皮秒减少到近似21 fs。维持数小时。紧同步使汽车信号的波动降低到散粒噪声极限。导致增强的汽车活细胞和聚合物珠的振动图像。(C)2002年美国光学学会。
We demonstrate a significant improvement in signal-to-noise ratio in coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two highly synchronized picosecond Ti:sapphire lasers. A temporal jitter between the pulse trains from the two independent commercial lasers is reduced from a few picoseconds to similar to21 fs. maintained over several hours. The tight synchronization brings the fluctuation of the CARS signal down to the shot-noise limit. leading to enhanced CARS vibrational images of living cells and polymer beads. (C) 2002 Optical Society of America.