Mycosis fungoides bullosa
Mycosis fungoides bullosa
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DOI：
10.1016/s0926-9959(96)00102-x
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发表时间：
1997-01-01
影响因子：
9.2
通讯作者：
Pereira, F
中科院分区：
文献类型：
--
作者：
Aranha, J;Cabecas, MD;Pereira, F
一个52岁的男性与蕈样肉芽肿大疱性，斑块阶段IIA，滤泡粘蛋白病和粟粒描述。该疾病开始于大约15年前，并随着光化学疗法（PUVA）诱导的缓解期以及后来的局部氮芥和etretinate的缓解期而发展。在其发展过程中依次出现水疱、脱发和粟粒疹。组织病理学除蕈样肉芽肿的特征外，还发现表皮下水疱和淋巴样细胞（CD 3（+））相关的滤泡粘蛋白病。蕈样肉芽肿的这些特定方面的病理生理进行了讨论。
A case of a 52-year-old man with mycosis fungoides bullosa, plaque-stage IIA, follicular mucinosis and milia is described. The disease started about 15 years ago and evolved with periods of remission induced by photochemotherapy (PUVA) and, later, by topical nitrogen mustard and etretinate. Vesiculobullous lesions, alopecia and milia sequentially appeared in the course of its evolution, Besides characteristic features of mycosis fungoides, histopathology revealed subepidermal vesicles and follicular mucinosis associated with lymphoid cells (CD3(+)). The pathophysiology of these particular aspects of the mycosis fungoides is discussed.