Ontology-based data integration between clinical and research systems.
Ontology-based data integration between clinical and research systems.
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DOI:
10.1371/journal.pone.0116656
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发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Ganslandt T
中科院分区:
文献类型:
--
作者:
Mate S;Köpcke F;Toddenroth D;Martin M;Prokosch HU;Bürkle T;Ganslandt T
Data from the electronic medical record comprise numerous structured but uncoded ele-ments, which are not linked to standard terminologies. Reuse of such data for secondary research purposes has gained in importance recently. However, the identification of rele-vant data elements and the creation of database jobs for extraction, transformation and loading (ETL) are challenging: With current methods such as data warehousing, it is not feasible to efficiently maintain and reuse semantically complex data extraction and trans-formation routines. We present an ontology-supported approach to overcome this challenge by making use of abstraction: Instead of defining ETL procedures at the database level, we use ontologies to organize and describe the medical concepts of both the source system and the target system. Instead of using unique, specifically developed SQL statements or ETL jobs, we define declarative transformation rules within ontologies and illustrate how these constructs can then be used to automatically generate SQL code to perform the desired ETL procedures. This demonstrates how a suitable level of abstraction may not only aid the interpretation of clinical data, but can also foster the reutilization of methods for un-locking it.
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影响因子:
2.9
作者:
Lee MK;Park HA;Min YH;Kim Y;Min HK;Ham SW
通讯作者:
Ham SW
DOI:
10.1136/amiajnl-2012-001312
发表时间:
2013-09
期刊:
Journal of the American Medical Informatics Association : JAMIA
影响因子:
--
作者:
Ethier JF;Dameron O;Curcin V;McGilchrist MM;Verheij RA;Arvanitis TN;Taweel A;Delaney BC;Burgun A
通讯作者:
Burgun A
影响因子:
2.7
作者:
Dugas, Martin;Lange, Matthias;Prokosch, Hans-Ulrich
通讯作者:
Prokosch, Hans-Ulrich
影响因子:
3
作者:
Cheung KH;Frost HR;Marshall MS;Prud'hommeaux E;Samwald M;Zhao J;Paschke A
通讯作者:
Paschke A
影响因子:
3.5
作者:
Breil B;Semjonow A;Müller-Tidow C;Fritz F;Dugas M
通讯作者:
Dugas M