Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature
Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature
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DOI：
10.1016/j.febslet.2007.09.039
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发表时间：
2007-10-16
期刊：
影响因子：
3.5
通讯作者：
Abe, Fumiyoshi
中科院分区：
文献类型：
--
作者：
Abe, Fumiyoshi
在生长条件改变为高静水压和低温后，研究了酿酒酵母的整体转录谱。这些谱在数量上非常相似，包含 561 个共同上调基因和 461 个共同下调基因。特别是，通常在缺氧下表达的 DANITIR 细胞壁甘露糖蛋白基因的表达在高压和低温下显着上调，表明转录调控网络存在重叠。为了支持甘露糖蛋白在细胞壁完整性中的作用，当在高压和低温下预孵育时，细胞获得了对 SDS、酶解酶和致死水平高压处理的抵抗力。 (c) 2007 年欧洲生化学会联合会。由 Elsevier B.V. 出版。保留所有权利。
Global transcriptional profiles of Saccharomyces cerevisiae were studied following changes in growth conditions to high hydrostatic pressure and low temperature. These profiles were quantitatively very similar, encompassing 561 co-upregulated genes and 461 co-downregulated genes. In particular, expression of the DANITIR cell wall mannoprotein genes, which are generally expressed under hypoxia, were markedly upregulated by high pressure and low temperature, suggesting the overlapping regulatory networks of transcription. In support of the role of mannoproteins in cell wall integrity, cells acquired resistance against treatment with SDS, Zymolyase and lethal levels of high pressure when preincubated under high pressure and low temperature. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.