An asymptomatic 61-year-old man with BCR-ABL-positive bone marrow following autologous transplantation for multiple myeloma.

An asymptomatic 61-year-old man with BCR-ABL-positive bone marrow following autologous transplantation for multiple myeloma.
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一名无症状的 61 岁男性,在接受多发性骨髓瘤自体移植后,骨髓 BCR-ABL 呈阳性。

DOI:
10.1002/ajh.21809
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发表时间:
2010
影响因子:
12.8
通讯作者:
Aster,JonC
Aster,JonC
中科院分区:
医学1区
文献类型:
--
作者:
Roper,Nitin;DeAngelo,DanielJ;Kuo,Frank;DalCin,Paola;Ghobrial,Irene;Aster,JonC

文献摘要

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A 61-year-old man treated with an autologous transplant for multiple myeloma was incidentally found to have a high level of BCR-ABL fusion gene-positive cells in his bone marrow. We describe the clinical decision-making process that led us to initiate therapy with imatinib, despite the absence of any clinical evidence of chronic myelogenous leukemia or other BCR-ABL associated hematologic malignancy.