Association of the BDNF Val66Met variation with obesity in women
Association of the BDNF Val66Met variation with obesity in women
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DOI：
10.1016/j.ymgme.2008.06.008
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发表时间：
2008-09-01
影响因子：
3.8
通讯作者：
Van Hul, Wim
中科院分区：
文献类型：
--
作者：
Beckers, Sigri;Peeters, Armand;Van Hul, Wim
脑源性神经营养因子（BDNF）已被暗示在调节食物摄入。在本研究中，我们对532名肥胖女性和197名健康女性对照的比利时队列进行了Val 66 Met多态性基因分型，并且首次能够显示66 Met等位基因与肥胖的相关性，至少在我们的女性队列中是这样。(C)2008年爱思唯尔公司All rights reserved.
Brain-derived neurotrophic factor (BDNF) has been implied in the regulation of food intake. In the present study, we genotyped the Val66Met polymorphism in a Belgian cohort of 532 obese women and 197 healthy female controls and were, for the first time, able to show an association of the 66Met allele with obesity, at least in our female cohort. (C) 2008 Elsevier Inc. All rights reserved.