Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique.
Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique.
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DOI：
10.1118/1.2903436
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发表时间：
2008-05
期刊：
影响因子：
3.8
通讯作者：
J. Xia;J. Lo;Kai Yang;C. Floyd;J. Boone
中科院分区：
文献类型：
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作者：
J. Xia;J. Lo;Kai Yang;C. Floyd;J. Boone
专用乳腺计算机断层扫描（CT）成像具有比传统乳房X线照片更好的病变检测潜力，特别是对于致密乳腺的女性。乳腺CT图像是用与单个乳腺的标准双视图乳腺X射线摄影相当的腺体剂量采集的。由于剂量的限制，重建体积具有不可忽略的量子噪声时，薄截面CT切片可视化。因此，期望在不损失空间分辨率的情况下减少重建的乳房体积中的噪声。在这项研究中，基于偏扩散方程（PDE）的去噪技术，专门用于乳腺CT应用在不同的步骤沿着重建过程，它被发现，去噪时，应用于投影数据，而不是重建数据表现更好。对比度细节体模的仿真结果表明，PDE技术优于维纳去噪以及自适应修剪均值滤波。当光子注量减少时，PDE技术相对于Wiener技术增加其性能优势。使用PDE技术，当剂量降低到双视图乳腺X射线摄影的40%时，使用对比度细节体模的病变检测灵敏度下降不到7%。对于主观评价，PDE技术被应用到两个人受试者的乳房数据集上获得的原型乳房CT系统。去噪后的图像具有吸引人的视觉特性，具有更低的噪声水平和改善的组织纹理，同时保持原始重建体积的清晰度。
Dedicated breast computed tomography (CT) imaging possesses the potential for improved lesion detection over conventional mammograms, especially for women with dense breasts. The breast CT images are acquired with a glandular dose comparable to that of standard two-view mammography for a single breast. Due to dose constraints, the reconstructed volume has a non-negligible quantum noise when thin section CT slices are visualized. It is thus desirable to reduce noise in the reconstructed breast volume without loss of spatial resolution. In this study, partial diffusion equation (PDE) based denoising techniques specifically for breast CT were applied at different steps along the reconstruction process and it was found that denoising performed better when applied to the projection data rather than reconstructed data. Simulation results from the contrast detail phantom show that the PDE technique outperforms Wiener denoising as well as adaptive trimmed mean filter. The PDE technique increases its performance advantage relative to Wiener techniques when the photon fluence is reduced. With the PDE technique, the sensitivity for lesion detection using the contrast detail phantom drops by less than 7% when the dose is cut down to 40% of the two-view mammography. For subjective evaluation, the PDE technique was applied to two human subject breast data sets acquired on a prototype breast CT system. The denoised images had appealing visual characteristics with much lower noise levels and improved tissue textures while maintaining sharpness of the original reconstructed volume.