A compact scanning probe for photoacoustic microscopy using ultrasonic actuator stage
A compact scanning probe for photoacoustic microscopy using ultrasonic actuator stage
复制标题
一种用于光声显微镜的紧凑型超声驱动扫描探针
DOI：
10.35848/1347-4065/ab7061
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发表时间：
2020-02
影响因子：
1.5
通讯作者：
Y. Yamaoka;Kaito Funatsu;Yuta Yoshidumi;Akari Kubo;Yusuke Notsuka;Eiji Takahashi
中科院分区：
文献类型：
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作者：
Y. Yamaoka;Kaito Funatsu;Yuta Yoshidumi;Akari Kubo;Yusuke Notsuka;Eiji Takahashi
近年来，光声显微镜(PAM)作为一种新型的医学成像手段引起了人们的关注，因为光声显微镜可以在高度散射的活体组织中显示几毫米深的结构，空间分辨率达到几十微米。为了将来在临床上使用PAM，缩小扫描探头的尺寸是必不可少的。在这项工作中，我们构建了一个带有微型超声致动器的PAM系统，使我们能够显著缩小扫描探头的尺寸(61 mm×50 mm×47 mm)。该系统的横向空间分辨率为∼4.4μm，16幅S/B超图像(80行A扫描)的成像速度可与传统的步进电机平台的PAM系统相当。
Recently, photoacoustic microscopy (PAM) has attracted attention as a novel modality for medical imaging, because PAM can visualize a-few-mm deep structures with a several-tens-micrometer spatial resolution in highly-scattering living tissues. For future use of PAM in clinics, downsizing of the scanning probe is essential. In this work, we constructed a PAM system with a miniature ultrasonic actuator that allowed us to significantly downsize the scanning probe (61 mm × 50 mm × 47 mm). We demonstrated lateral spatial resolution of ∼4.4 μm and imaging speed of 16 s/B-mode image (80 A-scan lines) in the proposed PAM system, being comparable to those of the conventional PAM system using stepping motor stage.