Congenital melanocytic nevi: Where are we now? Part II. Treatment options and approach to treatment
Congenital melanocytic nevi: Where are we now? Part II. Treatment options and approach to treatment
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DOI：
10.1016/j.jaad.2012.06.022
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发表时间：
2012-10-01
影响因子：
13.8
通讯作者：
Eisen, Daniel B.
中科院分区：
文献类型：
--
作者：
Ibrahimi, Omar A.;Alikhan, Ali;Eisen, Daniel B.
先天性黑色素细胞痣（CMN）的治疗通常有两个原因：（1）减少皮肤恶性黑色素瘤的机会和（2）出于美容原因。在过去的世纪中，文献中描述了大量CMN的治疗方法。这些方法包括切除术、磨皮术、刮宫术、化学换肤术、放射疗法、冷冻疗法、电外科手术和激光。只有低水平的证据支持这些方法，大型随机对照试验尚未发表。本文探讨了治疗争议，并根据现有的最佳证据提出建议。（J Am Acad Dermatol 2012;67：515.e1-13.）
Treatment of congenital melanocytic nevi (CMN) is generally undertaken for 2 reasons: (1) to reduce the chances of cutaneous malignant melanoma and (2) for cosmetic reasons. Over the past century, a large number of treatments for CMN have been described in the literature. These include excision, dermabrasion, curettage, chemical peels, radiation therapy, cryotherapy, electrosurgery, and lasers. Only low-level evidence supporting these approaches is available, and large randomized controlled trials have not been published. This article explores therapeutic controversies and makes recommendations based on the best available evidence. (J Am Acad Dermatol 2012;67:515.e1-13.)