Monolayer-protected nanoparticle-protein interactions.
Monolayer-protected nanoparticle-protein interactions.
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DOI：
10.1016/j.cbpa.2005.09.012
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发表时间：
2005-12
影响因子：
7.8
通讯作者：
C. You;Mrinmoy De;V. Rotello
中科院分区：
文献类型：
--
作者：
C. You;Mrinmoy De;V. Rotello
单层保护的纳米颗粒为靶向蛋白质和相关生物大分子提供了一种有吸引力的人工受体支架。在过去的两年里，多项努力集中在纳米颗粒-蛋白质相互作用的工程和应用上。这些研究包括蛋白质与纳米颗粒在水介质中的分子识别，蛋白质和纳米颗粒在溶液中或表面的自组装，以及基于纳米颗粒的蛋白质传感器的构建。
Monolayer-protected nanoparticles provide an appealing artificial receptor scaffold for targeting proteins and related biomacromolecules. During the past two years, multiple efforts have focused on the engineering and application of nanoparticle–protein interactions. These investigations include the molecular recognition of proteins with nanoparticles in aqueous media, self-assembly of proteins and nanoparticles either in solution or on surface, and construction of nanoparticle-based protein sensors.