Association between Topographic Features of the Retinal Nerve Fiber Bundle and Good Visual Acuity in Patients with Glaucoma
Association between Topographic Features of the Retinal Nerve Fiber Bundle and Good Visual Acuity in Patients with Glaucoma
复制标题
DOI：
10.1080/02713683.2021.1912782
复制
发表时间：
2021-04-17
影响因子：
2
通讯作者：
Nakazawa, Toru
中科院分区：
文献类型：
--
作者：
Takahashi, Naoki;Omodaka, Kazuko;Nakazawa, Toru
目的：维持青光眼患者的视力是防止视觉质量恶化的重要组成部分。我们根据光学相干断层扫描（OCT）获得的正面图像确定了与视力密切相关的乳头状黄斑束（PMB）的特定区域。（年龄：61.3 +/- 13.0岁，男：女= 9：12，Humphrey场分析仪-测量的平均偏差：-19.9 +/- 6.5 dB），最佳矫正视力良好（20/20或更高），剩余PMB的最大宽度不超过垂直椎间盘直径的一半。正面图像来源于用DRI-OCT（Triton，Topcon）制作的12 x 9 mm宽扫描图像。通过识别椎间盘中心和中心凹线（DFL）并在图像之间对齐来创建平均正面图像。然后，我们测量剩余的PMB的频率在10 μ m的间隔沿着垂直线相交的DFL在其中点。最后，我们在一个更大的患者组中使用了逻辑分析来识别低BCVA的青光眼病例（
Purpose: Maintaining visual acuity in glaucoma patients is an important part of preventing the deterioration of quality of vision. We identified specific areas of the papillomacular bundle (PMB) that were strongly associated with visual acuity, based on en-face images derived from optical coherence topography (OCT) wide scans.Methods: The study recruited 23 eyes of 21 glaucoma patients (age: 61.3 +/- 13.0 years, M: F = 9:12, Humphrey field analyzer-measured mean deviation: -19.9 +/- 6.5 dB) with good best-corrected visual acuity (20/20 or more) and a remaining PMB with a maximum width no more than half that of the vertical disc diameter. En-face images were derived from 12 x 9 mm wide-scan images made with DRI-OCT (Triton, Topcon). Averaged en-face images were created by identifying the disc center and fovea line (DFL) and aligning it between images. We then measured the frequency of remaining PMB at 10 mu m intervals along a vertical line intersecting the DFL at its midpoint. Finally, we used a logistic analysis in a much larger group of patients to identify cases of glaucoma with low BCVA (