A Nationwide Survey Aimed at Establishing an Appropriate Long-Term Storage and Management System for Fertility Preserving Specimens in Japan
A Nationwide Survey Aimed at Establishing an Appropriate Long-Term Storage and Management System for Fertility Preserving Specimens in Japan
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日本开展一项全国性调查，旨在建立适当的生育力保存标本长期储存和管理系统
DOI：
10.1089/jayao.2021.0209
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发表时间：
2022
影响因子：
2
通讯作者：
Suzuki Nao
中科院分区：
文献类型：
--
作者：
Maezawa Tadashi;Takae Seido;Takeuchi Hiroki;Takenaka Motoki;Ota Kuniaki;Horie Akihito;Suzuki Tatsuya;Takai Yasushi;Kimura Fuminori;Furui Tatsuro;Ikeda Tomoaki;Suzuki Nao
目的：随着癌症治疗结果的改善，对保留生育能力的需求持续增长。与传统的生育治疗相比，保存生育能力的标本保存期更长；因此，需要一个强大的保存标本管理系统。我们在日本进行了第一次全国范围内关于精子保存机构冷冻标本管理的调查。方法：向130家生育机构发出问卷。主要结果包括储存经理的正式职位、设施关闭时的支持系统、灾难应对措施、液氮储存容器的管理和操作制度、保存成本和确认继续储存意向的方法。结果：应答率为63.8%。设施总监最常担任仓储经理(59.0%)。在设施关闭的情况下，20.5%的人有批准的转移地点；59.0%的人没有做出任何决定。在液氮容器管理中，83.1%的人定期补充液氮，65.1%的人定期检查液氮的数量，16.9%的人有报警监控系统。在灾难应对措施方面，70.9%的人采取了标本保护措施。结论：本次调查揭示了标本长期保存设施存在差距等问题。因此，应建立育性保存设施的管理标准。
Purpose:The demand for fertility preservation continues to grow as cancer treatment outcomes improve. The specimen storage period is longer for fertility preservation than for conventional fertility treatment; therefore, a robust management system for stored specimens is required. We conducted the first national survey in Japan on the management of cryopreserved specimens in fertility preservation facilities.Methods:Questionnaires were mailed to 130 fertility preservation facilities. Primary outcomes included the official position of the storage manager, support system in case of facility closure, disaster countermeasures, management and operating system for liquid nitrogen storage containers, preservation costs, and method to confirm the intention to continue storage.Results:The response rate was 63.8%. The facility director most commonly functioned as the storage manager (59.0%). In case of facility closure, 20.5% had an approved transfer site; 59.0% had not made any decisions. In the management of liquid nitrogen containers, 83.1% regularly replenished the liquid nitrogen, 65.1% regularly checked the amount, and 16.9% had alarm monitoring systems. Regarding disaster countermeasures, 70.9% had taken measures to protect specimens.Conclusion:This survey revealed issues such as disparities among facilities regarding long-term specimen storage systems. Accordingly, management standards for fertility preservation facilities should be established.