RADSeq: next-generation population genetics

RADSeq: next-generation population genetics
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DOI:
10.1093/bfgp/elq031
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发表时间:
2010-12-01
影响因子:
4
通讯作者:
Blaxter, Mark W.
Blaxter, Mark W.
中科院分区:
生物学3区
文献类型:
--
作者:
Davey, John L.;Blaxter, Mark W.

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Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations. However, genome-scale population genetic studies have been accessible only to well-funded model systems. Restriction-site associated DNA sequencing, a method that samples at reduced complexity across target genomes, promises to deliver high resolution population genomic data-thousands of sequenced markers across many individuals-for any organism at reasonable costs. It has found application in wild populations and non-traditional study species, and promises to become an important technology for ecological population genomics.