The ageing brain: normal and abnormal memory
The ageing brain: normal and abnormal memory
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DOI：
10.1098/rstb.1997.0152
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发表时间：
1997-11-29
期刊：
影响因子：
--
通讯作者：
Albert, MS
中科院分区：
文献类型：
--
作者：
Albert, MS
随着年龄的增长，大多数人的学习和记忆能力都会下降。对各个年龄段的健康老年人的大脑结构和功能的检查表明，大脑中存在重大变化，这些变化似乎与记忆的改变有关。与年龄相关的变化相关的认知和神经生物学改变的性质与阿尔茨海默病等痴呆症的早期阶段有很大不同。这些差异对潜在的干预策略有影响。
With advancing-age, the majority of individuals experience declines in their ability to learn and remember. An examination of brain structure and function in healthy older persons across the age range indicates that there are substantial changes in the brain that appear to be related to alterations in memory. The nature of the cognitive and neurobiological alterations associated with age-related change is substantially different from that seen in the early stages of a dementing illness, such as Alzheimer's disease. These differences have implications for potential intervention strategies.