Syringe Sharing and HIV Incidence Among Injection Drug Users and Increased Access to Sterile Syringes
Syringe Sharing and HIV Incidence Among Injection Drug Users and Increased Access to Sterile Syringes
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DOI：
10.2105/ajph.2009.178467
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发表时间：
2010-08-01
影响因子：
12.7
通讯作者：
Wood, Evan
中科院分区：
文献类型：
--
作者：
Kerr, Thomas;Small, Will;Wood, Evan
目标。我们评估了注射器交换计划 (SEP) 政策对注射吸毒者中艾滋病毒危险行为率和艾滋病毒发病率的影响。方法。我们使用多元广义估计方程和 Cox 回归方法，研究了不列颠哥伦比亚省温哥华市 1228 名注射吸毒者的前瞻性队列中的注射器借用、注射器借出和艾滋病毒发病率。结果。我们观察到，随着标准必要专利政策的改变，注射器借贷率（从 1998 年的 20.1% 下降到 2003 年的 9.2%）和注射器贷款率（从 1998 年的 19.1% 下降到 2003 年的 6.8%）大幅下降。这些下降与从非传统 SEP 来源获取无菌注射器的参与者比例在统计学上显着增加同时发生（P
Objectives. We assessed the effects of syringe exchange program (SEP) policy on rates of HIV risk behavior and HIV incidence among injection drug users.Methods. Using a multivariate generalized estimating equation and Cox regression methods, we examined syringe borrowing, syringe lending, and HIV incidence among a prospective cohort of 1228 injection drug users in Vancouver, British Columbia.Results. We observed substantial declines in rates of syringe borrowing (from 20.1% in 1998 to 9.2% in 2003) and syringe lending (from 19.1% in 1998 to 6.8% in 2003) following SEP policy change. These declines coincided with a statistically significant increase in the proportion of participants accessing sterile syringes from nontraditional SEP sources (P