Diversity among French Bacillus anthracis isolates

Diversity among French Bacillus anthracis isolates
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DOI:
10.1128/jcm.40.12.4732-4734.2002
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发表时间:
2002-12-01
影响因子:
9.4
通讯作者:
Keim, P
Keim, P
中科院分区:
医学2区
文献类型:
--
作者:
Fouet, AS;Smith, KL;Keim, P

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尽管动物炭疽人畜共患病的爆发在法国仍然经常发生,但人们对它们之间的流行病学联系知之甚少。我们对来自法国的 50 个炭疽杆菌分离株使用了八位点多位点可变数量串联重复分析分型技术。有八种不同的基因型属于两个不同的基因簇。观察到区域菌株模式,B2 基因型在法国南部普遍存在,而 Ala 基因型仅在法国北部发现。
While outbreaks of animal anthrax zoonoses still regularly occur in France, little is known about the epidemiology links between them. We have used the eight-locus multilocus variable-number tandem repeat analysis typing technique against a collection of 50 Bacillus anthracis isolates from France. There were eight distinct genotypes belonging to two dissimilar genetic clusters. Regional strain patterns were observed, with the B2 genotypes prevalent in southern France and the Ala genotypes found only in northern France.