Sensitivity of distortion product otoacoustic emissions in noise-exposed chinchillas.
Sensitivity of distortion product otoacoustic emissions in noise-exposed chinchillas.
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DOI：
10.3766/jaaa.16.2.2
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发表时间：
2005-02-01
影响因子：
1.2
通讯作者：
Hamernik, Roger P
中科院分区：
文献类型：
--
作者：
Davis, Bob;Qiu, Wei;Hamernik, Roger P
本研究调查了 12 只暴露于噪声的龙猫群体中少量外毛细胞 (OHC) 损失对畸变产物耳声发射 (DPOAE) 水平和诱发潜在永久阈值漂移 (PTS) 的影响。组平均 DPOAE 水平在 PTS 低于 8 dB 和 OHC 损失 15% 的情况下下降了约 15 dB，这表明 DPOAE 可以检测潜在的耳蜗病理（即 OHC 损伤/损失），尽管存在正常至接近正常阈值。 DPOAE 在检测 OHC 损失方面的敏感性使得该测试方法适合诊断感音神经性听力损伤，特别是当异常听觉症状（即言语辨别问题）与临床环境中的正常听力图相关且作为听力保护计划的一部分时。
The present study investigates the effect of small amounts of outer hair cell (OHC) loss on distortion product otoacoustic emission (DPOAE) levels and evoked potential permanent threshold shifts (PTS) in a population of 12 noise-exposed chinchillas. The group mean DPOAE level, which decreased by up to approximately 15 dB in the presence of less than 8 dB PTS and 15% OHC loss, indicates that DPOAEs can detect an underlying cochlear pathology (i,e., OHC damage/loss) despite the presence of normal to near normal thresholds. The sensitivity of DPOAEs in detecting OHC loss makes this test measure suited for diagnosing sensorineural hearing impairment, particularly when abnormal auditory symptoms (i.e., speech discrimination problems) are associated with a normal audiogram in the clinical setting and as part of a hearing conservation program.