Pattern recognition receptors and signaling in plant-microbe interactions
Pattern recognition receptors and signaling in plant-microbe interactions
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水稻长链非编码RNA多聚腺苷酸化的应激反应调控
DOI：
10.1111/tpj.13808
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发表时间：
2018-02-01
期刊：
影响因子：
7.2
通讯作者：
Yasuda, Shigetaka
中科院分区：
文献类型：
--
作者：
Saijo, Yusuke;Loo, Eliza Po-iian;Yasuda, Shigetaka
植物仅仅依靠每个细胞的先天免疫来应对环境中的各种微生物。微生物和宿主损伤相关分子模式的细胞外识别导致第一层诱导性防御，称为模式触发免疫（PTI）。在植物中，模式识别受体（PRR）的日期描述的都是膜相关的受体样激酶或受体样蛋白，反映了植物感染微生物的质外体定殖的流行。越来越多的激发子活性模式和PRRs的库存表明，他们中的大量的是有限的一定范围内的植物组/物种，指向动态和收敛的模式识别特异性的进化。除了PRR信号传导的常见分子原理之外，最近的研究已经揭示了PRR在其功能和调节机制方面的实质性多样化。这有助于在自然感染中赋予整个PTI系统鲁棒性和可塑性，其中不同的PRR同时参与并面临微生物攻击。我们回顾了PRR介导的病原体识别和抗病性的功能意义和分子基础，以及PRR在与有益或有害微生物的稳态关联中的新兴作用。
Plants solely rely on innate immunity of each individual cell to deal with a diversity of microbes in the environment. Extracellular recognition of microbe- and host damage-associated molecular patterns leads to the first layer of inducible defenses, termed pattern-triggered immunity (PTI). In plants, pattern recognition receptors (PRRs) described to date are all membrane-associated receptor-like kinases or receptor-like proteins, reflecting the prevalence of apoplastic colonization of plant-infecting microbes. An increasing inventory of elicitor-active patterns and PRRs indicates that a large number of them are limited to a certain range of plant groups/species, pointing to dynamic and convergent evolution of pattern recognition specificities. In addition to common molecular principles of PRR signaling, recent studies have revealed substantial diversification between PRRs in their functions and regulatory mechanisms. This serves to confer robustness and plasticity to the whole PTI system in natural infections, wherein different PRRs are simultaneously engaged and faced with microbial assaults. We review the functional significance and molecular basis of PRR-mediated pathogen recognition and disease resistance, and also an emerging role for PRRs in homeostatic association with beneficial or commensal microbes.