Relationship Between Fibromyalgia and Obesity in Pain, Function, Mood, and Sleep
Relationship Between Fibromyalgia and Obesity in Pain, Function, Mood, and Sleep
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DOI：
10.1016/j.jpain.2010.03.006
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发表时间：
2010-12-01
期刊：
影响因子：
4
通讯作者：
Fine, Perry G.
中科院分区：
文献类型：
--
作者：
Okifuji, Akiko;Donaldson, Gary W.;Fine, Perry G.
纤维肌痛综合征（FMS）是一种常见的致残性慢性疼痛疾病，过去的研究表明肥胖是一种常见的合并症，并且可能与FMS的严重程度有关。本研究的主要目的是评估FMS与肥胖在FMS相关的多个领域中的关系。共有215名FMS患者完成了一套自我报告清单，以评估FMS相关症状，并进行了压痛点（TP）检查、体能测试和7天的家庭睡眠评估。我们的样本中有47%的人肥胖，另外30%的人超重。肥胖与压痛点触诊的疼痛敏感性（尤其是下体区域）显著相关，体力和下体柔韧性降低，睡眠时间缩短。研究结果证实，肥胖是FMS的普遍合并症，可能会导致问题的严重性。本文讨论了这种关系的潜在机制。我们发现肥胖在FMS患者中很常见，大约有一半的患者肥胖，另外30%的患者超重。我们还发现，FMS患者的肥胖与更大的疼痛敏感性、更差的睡眠质量、体力和柔韧性下降有关。结果表明，肥胖可能会导致FMS，体重管理可能需要纳入治疗(c) 2010年由美国疼痛协会
Fibromyalgia syndrome (FMS) is a prevalent and disabling chronic pain disorder Past research suggests that obesity is a common comorbidity and may be related to the severity of FMS The main objective of the present study was to evaluate the relationships between FMS and obesity in the multiple FMS-related domains hyperalgesia, symptoms, physical abilities, and sleep A total of 215 FMS patients completed a set of self-report inventories to assess FMS-related symptoms and underwent the tender point (TP) examination, physical performance testing, and 7-day home sleep assessment Forty-seven percent of our sample was obese and an additional 30% was overweight Obesity was related significantly to greater pain sensitivity to TP palpation particularly in the lower body areas, reduced physical strength and lower-body flexibility, shorter sleep duration, and greater restlessness during sleep The results confirmed that obesity is a prevalent comorbidity of FMS that may contribute to the severity of the problem Potential mechanisms underlying the relationship are discussedPerspective This report presents how obesity may be interrelated to fibromyalgia pain, disability and sleep We found that obesity is common in FMS Approximately half of our patients were obese and an additional 30% were overweight We also found that obesity in FMS was associated with greater pain sensitivity, poorer sleep quality, and reduced physical strength and flexibility The results suggest that obesity may aggregate FMS and weight management may need to be incorporated into treatments (c) 2010 by the American Pain Society