TransportDB: a relational database of cellular membrane transport systems

TransportDB: a relational database of cellular membrane transport systems
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DOI:
10.1093/nar/gkh016
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发表时间:
2004-01-01
影响因子:
14.9
通讯作者:
Paulsen, IT
Paulsen, IT
中科院分区:
生物学2区
文献类型:
--
作者:
Ren, QH;Kang, KH;Paulsen, IT

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TransportDB(http://www.membranetransport.org))是一个关系型数据库,用于描述已有完整基因组序列的生物体中预测的细胞膜转运蛋白。根据膜的拓扑结构、蛋白质家族、生物能量学和底物特性,对每种生物的全套膜转运系统进行了鉴定和分类。创建网页是为了提供用户友好的界面,以便轻松访问、查询和下载数据。还提供了其他功能,例如针对已知转运蛋白序列的BLAST搜索工具、来自不同生物的转运蛋白系统的比较以及单个转运蛋白家族的系统发育树。TransportDB将定期更新从新测序的基因组中获得的数据。
TransportDB (http://www.membranetransport.org) is a relational database designed for describing the predicted cellular membrane transport proteins in organisms whose complete genome sequences are available. For each organism, the complete set of membrane transport systems was identified and classified into different types and families according to putative membrane topology, protein family, bioenergetics and substrate specificities. Web pages were created to provide user-friendly interfaces to easily access, query and download the data. Additional features, such as a BLAST search tool against known transporter protein sequences, comparison of transport systems from different organisms and phylogenetic trees of individual transporter families are also provided. TransportDB will be regularly updated with data obtained from newly sequenced genomes.