Viruses at Solid Water Interfaces: A Systematic Assessment of Interactions Driving Adsorption
Viruses at Solid Water Interfaces: A Systematic Assessment of Interactions Driving Adsorption
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DOI：
10.1021/acs.est.5b04644
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发表时间：
2016-01-19
影响因子：
11.4
通讯作者：
Sander, Michael
中科院分区：
文献类型：
--
作者：
Armanious, Antonius;Aeppli, Meret;Sander, Michael
吸附到固体-水界面是自然和工程系统中控制水性病毒命运的主要过程。然而，不同的相互作用力对吸附的相对贡献及其对病毒理化性质的依赖性仍然知之甚少。在这里，我们系统地研究了四个噬菌体（MS 2，FR，GA和Q β）的吸附到五个模型表面与不同的表面化学和三个溶解的有机物吸附层，作为溶液pH值和离子强度的函数，使用石英晶体微天平与耗散监测。选择的病毒具有相似的大小和形状，但不同的表面电荷，极性和地形，如通过模拟病毒衣壳中氨基酸的分布所确定的。病毒-吸附剂相互作用受长程静电和疏水效应的有利贡献控制，短程货车德瓦尔斯相互作用是次要的。空间效应取决于病毒和吸附剂表面的地形不规则性。测试病毒的吸附特性的差异成功地与其衣壳表面性质的差异相关联。除了确定主要的相互作用力，这项工作突出了可计算的病毒表面电荷和极性描述符预测病毒吸附到固体-水界面的潜力。
Adsorption to solid-water interfaces is a major process governing the fate of waterborne viruses in natural and engineered systems. The relative contributions of different interaction forces to adsorption and their dependence on the physicochemical properties of the viruses remain, however, only poorly understood. Herein, we systematically studied the adsorption of four bacteriophages (MS2, fr, GA, and Q beta) to five model surfaces with varying surface chemistries and to three dissolved organic matter adlayers, as a function of solution pH and ionic strength, using quartz crystal microbalance with dissipation monitoring. The viruses were selected to have similar sizes and shapes but different surface charges, polarities, and topographies, as identified by modeling the distributions of amino acids in the virus capsids. Virus-sorbent interactions were governed by long-ranged electrostatics and favorable contributions from the hydrophobic effect, and shorter-ranged van der Waals interactions were of secondary importance. Steric effects depended on the topographic irregularities on both the virus and sorbent surfaces. Differences in the adsorption characteristics of the tested viruses were successfully linked to differences in their capsid surface properties. Besides identifying the major interaction forces, this work highlights the potential of computable virus surface charge and polarity descriptors to predict virus adsorption to solid-water interfaces.