Homeostatic sleep regulation in habitual short sleepers and long sleepers
Homeostatic sleep regulation in habitual short sleepers and long sleepers
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DOI：
10.1152/ajpregu.1996.270.1.r41
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发表时间：
1996-01-01
影响因子：
2.8
通讯作者：
Borbely, AA
中科院分区：
文献类型：
--
作者：
Aeschbach, D;Cajochen, C;Borbely, AA
通过研究长睡眠者的睡眠结构和睡眠脑电图（EEG），研究了长睡眠者（睡眠时间< 6 h, n = 9）和习惯性短睡眠者（睡眠时间< 6 h, n = 7）在基线条件下的睡眠结构和睡眠脑电图（EEG）。在每次睡眠时间中，长睡眠者的总睡眠时间比短睡眠者多bb1 3 h。睡眠剥夺对长睡眠者的睡眠潜伏期和快速眼动（REM）睡眠密度的影响大于短睡眠者。睡眠缺失后，长睡眠者非快速眼动睡眠时脑电图慢波活动（SWA；频谱功率密度在0.75 ~ 4.5 Hz范围内）的增强幅度（47%）大于短睡眠者（19%）。这种SWA反应的差异是通过基于不同睡眠持续时间的睡眠调节双过程模型预测的。结果表明，短睡眠者的“非快速眼动睡眠压力”高于长睡眠者。然而，这两组在稳态睡眠调节机制方面没有差异。
Homeostatic sleep regulation in habitual short sleepers (sleep episode < 6 h, n = 9) and long sleepers (>9 h, n = 7) was investigated by studying their sleep structure and sleep electroencephalogram (EEG) during baseline conditions and after prolonging their habitual waking time by 24 h. In each sleep episode, total sleep time was >3 h longer in the long sleepers than in the short sleepers. Sleep deprivation decreased sleep latency and rapid eye movement (REM) density in REM sleep more in long sleepers than in short sleepers. The enhancement of EEG slow-wave activity (SWA; spectral power density in the 0.75-4.5 Hz range) in non-REM sleep after sleep loss was larger in long sleepers (47%) than in short sleepers (19%). This difference in the SWA response was predicted by the two-process model of sleep regulation on the basis of the different sleep durations. The results indicate that short sleepers live under a higher ''non-REM sleep pressure'' than long sleepers. However, the two groups do not differ with respect to the homeostatic sleep regulatory mechanisms.