HEMODYNAMIC DETERMINANTS OF OXYGEN CONSUMPTION OF THE HEART WITH SPECIAL REFERENCE TO THE TENSION-TIME INDEX
HEMODYNAMIC DETERMINANTS OF OXYGEN CONSUMPTION OF THE HEART WITH SPECIAL REFERENCE TO THE TENSION-TIME INDEX
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DOI：
10.1152/ajplegacy.1957.192.1.148
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发表时间：
1958-01-01
影响因子：
--
通讯作者：
MACRUZ, R
中科院分区：
文献类型：
--
作者：
SARNOFF, SJ;BRAUNWALD, E;MACRUZ, R
在分离的、代谢支持的、无衰竭的犬心脏中，确定了心肌氧利用的血流动力学决定因素。主要决定因素是心肌产生的总张力，由收缩压曲线下的面积（张力-时间指数）表示。讨论了这些发现对理解衰竭心脏的低效率的意义以及由此增加的拉普拉斯定律的重要性。
The hemodynamic determinants of myocardial oxygen utilization were ascertained in the isolated, metabolically supported, nonfailing canine heart. The primary determinant was found to be the-total tension developed by the myocardium as indicated by the area beneath the systolic pressure curve (Tension-Time Index). The significance of these findings for the understanding of the low efficiency of the failing heart and the consequently increased importance of Laplace''s law are discussed.