Efficacy of Acupuncture for Primary Insomnia: A Randomized Controlled Clinical Trial
Efficacy of Acupuncture for Primary Insomnia: A Randomized Controlled Clinical Trial
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DOI：
10.1155/2013/163850
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发表时间：
2013-01-01
影响因子：
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通讯作者：
Cheng, Jin-Lian
中科院分区：
文献类型：
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作者：
Guo, Jing;Wang, Lin-Peng;Cheng, Jin-Lian
目标.观察针刺治疗对原发性失眠症患者睡眠质量和日间功能的影响。方法.本研究是一项双模拟、单盲、随机、安慰剂对照临床试验。将180例原发性失眠症患者随机分为3组：真针组（Verum）加安慰剂治疗;艾司唑仑组（Estazolam）加假针治疗;假针组（Sham）加安慰剂治疗。采用匹兹堡睡眠质量指数（PSQI）、埃普沃思嗜睡量表（ESS）和36项健康状况调查问卷（SF-36）进行评定。结果与治疗前基线相比，三组均显示出显著改善。与其他两组相比，Verum组报告了改善的睡眠质量（SQ）和活力（VT），减少日间功能障碍（DD）和嗜睡（ESS评分）。从治疗期至试验结束，保持差异。讨论维鲁针灸似乎更有效地提高睡眠质量和日间功能比假针灸和艾司唑仑。试验注册。试验注册于ClinicalTrials.gov ISRCTN 12585433。
Objectives. To investigate the six-week influence of acupuncture on sleep quality and daytime functioning in primary insomnia. Methods. The study was a double-dummy, single-blinded, randomized, placebo-controlled clinical trial. A total of 180 patients with primary insomnia were randomly assigned to 3 groups: verum group underwent verum acupuncture plus placebo; estazolam group underwent estazolam plus sham acupuncture; sham group underwent sham acupuncture plus placebo. The outcome was measured by Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and the 36-item short-form health survey (SF-36). Results. The three groups showed significant improvement compared with the pretreatment baseline. Compared with the other two groups, the verum group reported improved sleep quality (SQ) and vitality (VT), decreased daytime dysfunction (DD) and sleepiness (ESS score). The differences were kept from the treatment period to the end of the trial. Discussion. Verum acupuncture appeared to be more effective in increasing sleep quality and daytime functioning than sham acupuncture and estazolam. Trial Registration. The trial is registeded with ClinicalTrials.gov ISRCTN12585433.