Improved diffusion-weighted single-shot echo-planar imaging (EPI) in stroke using Sensitivity Encoding (SENSE)
Improved diffusion-weighted single-shot echo-planar imaging (EPI) in stroke using Sensitivity Encoding (SENSE)
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DOI：
10.1002/mrm.1226
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发表时间：
2001-09-01
影响因子：
3.3
通讯作者：
Fazekas, F
中科院分区：
文献类型：
--
作者：
Bammer, R;Keeling, SL;Fazekas, F
扩散加权单次激发计划成像(SshEPI)是诊断中风患者的重要工具之一，但存在着众所周知的伪影。因此，sshEPI与敏感性编码(SENSE)相结合，进一步提高了EPI在卒中成像中的潜力。对8名健康志愿者和连续8例疑似卒中患者(N=8)进行扩散加权正义-sshEPI检查，检查采用不同折减因子(1.0小于或等于R小于或等于3.0)。此外，还包括高分辨率扩散加权SENSE-sshEPI扫描。所有检查都是诊断性的，而且质量比传统的sshEPI更好。没有可辨认的鬼影或混叠伪影，与EPI相关的图像失真明显减少。化学位移伪影和涡流引起的图像扭曲仍然存在，尽管程度明显较小。测量的方向相关扩散系数和各向同性扩散值与以前的结果相当，但波动较小。我们已经证明了弥散加权正义-sshEPI在亚急性卒中患者中的技术可行性和临床适用性。由于k空间的遍历速度更快，这种新技术能够减少典型的EPI伪影，提高空间分辨率，同时保持对整体运动的不敏感。(C)2001年Wiley-Liss，Inc.
Diffusion-weighted single-shot EPI (sshEPI) is one of the most important tools for the diagnostic assessment of stroke patients, but it suffers from well known artifacts. Therefore, sshEPI was combined with SENSitivity Encoding (SENSE) to further increase EPI's potential for stroke imaging. Eight healthy volunteers and a consecutive series of patients (N = 8) with suspected stroke were examined with diffusion-weighted SENSE-sshEPI using different reduction factors (1.0 less than or equal to R less than or equal to 3.0). Additionally, a high-resolution diffusion-weighted SENSE-sshEPI scan was included. All examinations were diagnostic and of better quality than conventional sshEPI. No ghostings or aliasing artifacts were discernible, and EPI-related image distortions were markedly diminished. Chemical shift artifacts and eddy current-induced image warping were still present, although to a markedly smaller extent. Measured direction-dependent diffusion-coefficients and isotropic diffusion values were comparable to previous findings but showed less fluctuation. We have demonstrated the technical feasibility and clinical applicability of diffusion-weighted SENSE-sshEPI in patients with subacute stroke. Because of the faster k-space traversal, this novel technique is able to reduce typical EPI artifacts and increase spatial resolution while simultaneously remaining insensitive to bulk motion. (C) 2001 Wiley-Liss, Inc.