Cognitive profiles of boys with the fragile X syndrome.
Cognitive profiles of boys with the fragile X syndrome.
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患有脆性 X 综合征的男孩的认知概况。
DOI：
10.1002/ajmg.1320300118
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发表时间：
1988
期刊：
影响因子：
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通讯作者：
Debra Altshul
中科院分区：
文献类型：
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作者：
M. B. Kemper;R. Hagerman;R. Hagerman;Debra Altshul
用考夫曼儿童评估系统（K-ABC）对20名患有脆性X（或马丁-贝尔）综合征的男孩进行了测试，结果显示出一种一致的优势和劣势模式，这可能有助于预测细胞遗传学测试中脆性X阳性结果。该K-ABC模式包括：1)顺序量表得分低于同时量表得分；2)心理加工综合得分低于成就量表得分；3)空间记忆子测试得分低于矩阵类比子测试得分；4)算术子测试分数小于成就子测试分数的平均值。一个由20名男孩组成的对照组没有显示出这种模式。对于表现为学习障碍、多动症、注意力问题或轻度智障的男孩，应考虑进行K-ABC测试。具有K-ABC脆性X型四种特征中的三种或四种特征的男孩应考虑进行医学评估和细胞遗传学检测。
Testing 20 boys with the fragile X (or Martin-Bell) syndrome with the Kaufman Assessment Battery for Children (K-ABC) showed a consistent pattern of strengths and weaknesses that may be useful in predicting a fragile X positive result from cytogenetic testing. This K-ABC pattern included 1) Sequential Scale score less than the Simultaneous Scale score; 2) Mental Processing Composite less than the Achievement Scale score; 3) Spatial Memory subtest score less than the Matrix Analogies subtest score; and 4) Arithmetic subtest score less than the mean of the Achievement subtest scores. A comparison group of 20 boys did not demonstrate such a pattern. Testing with the K-ABC should be considered for boys who present as learning disabled, hyperactive with attentional problems, or mildly retarded. Boys with three or four of the four features of the K-ABC fragile X pattern should be considered for medical evaluation and cytogenetic testing.