Evolution of genetic diversity using networks: the human gut microbiome as a case study
Evolution of genetic diversity using networks: the human gut microbiome as a case study
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DOI：
10.1111/j.1469-0691.2012.03856.x
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发表时间：
2012-07-01
影响因子：
14.2
通讯作者：
Lopez, P.
中科院分区：
文献类型：
--
作者：
Bapteste, E.;Bicep, C.;Lopez, P.
临床微生物感染2012年；18年(补充4)：4043摘要为了研究复杂的微生物群落及其相关的可移动遗传元素，如人类肠道微生物组，进化学家可以利用共享的序列网络来探索它们的遗传多样性。特别是，对肠道微生物组基因网络中显著结构的检测可以帮助确定群落内的重要功能，并将简化来自各种来源(人、猿、鼠等)的微生物组的数据集的比较。在一次分析中。
Clin Microbiol Infect 2012; 18 (Suppl. 4): 4043 Abstract In order to study complex microbial communities and their associated mobile genetic elements, such as the human gut microbiome, evolutionists could explore their genetic diversity with shared sequence networks. In particular, the detection of remarkable structures in gene networks of the gut microbiome could serve to identify important functions within the community, and would ease comparison of data sets from microbiomes of various sources (human, ape, mouse etc.) in a single analysis.