Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
复制标题
使用单片有源像素传感器系统进行实时上游放射治疗验证
DOI：
10.1088/1742-6596/1662/1/012034
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Velthuis J
中科院分区：
文献类型：
--
作者：
Velthuis J
调强放射治疗是一种广泛使用的技术，可准确靶向困难部位的癌性肿瘤。随着治疗变得越来越复杂，需要开发新的方法来监测它们。单片有源像素传感器是在治疗期间提供上游光束监测的可行候选者。基于 MAPS 的系统可以做得足够薄，衰减小于 1%。我们已经证明，对于每秒采样 34 次的 5 毫米宽叶片，等中心处的叶片位置分辨率低于 130 微米。我们已经证明，可以确定治疗光子产生的信号，从而确定患者的剂量。此外，该传感器在 MR 直线加速器内运行良好，即使在充满挑战的环境中也能验证叶片位置。
Intensity modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations. As treatments are becoming more complex, new methods need to be developed to monitor them. Monolithic active pixel sensors are a viable candidate for providing upstream beam monitoring during treatment. A MAPS based system can be made thin enough to have less than 1% attenuation. We have already demonstrated leaf position resolutions below 130µm at the iso-centre for 5mm wide leaves sampled 34 times per second. We have shown that the signal due to therapeutic photons can be determined and thus the dose in patient. Furthermore, the sensor works well inside an MR-linac, allowing leaf position verification even in that challenging environment.
影响因子：
3.5
作者：
Vial, Philip;Oliver, Lyn;Baldock, Clive
通讯作者：
Baldock, Clive