Serosurvey for Crimean-Congo hemorrhagic fever virus infections in ruminants in Katanga province, Democratic Republic of the Congo
Serosurvey for Crimean-Congo hemorrhagic fever virus infections in ruminants in Katanga province, Democratic Republic of the Congo
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DOI：
10.1016/j.ttbdis.2017.07.001
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发表时间：
2017-01-01
影响因子：
3.2
通讯作者：
Groschup, Martin H.
中科院分区：
文献类型：
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作者：
Sas, Miriam A.;Mertens, Marc;Groschup, Martin H.
许多非洲国家都发现了克里米亚-刚果出血热病毒（CCHFV）。不幸的是，人们对包括刚果民主共和国 (DRC) 在内的大多数国家目前的 CCHFV 情况知之甚少。 50 多年来，刚果民主共和国已发现 3 例人类 CCHF 病例，但迄今为止尚未进行血清流行病学调查。为了确定 CCHFV 特异性抗体的流行情况，我们检测了来自刚果民主共和国南部省份加丹加的 838 份牛、山羊和绵羊的血清样本。在卡米纳和卢本巴希两个采样点之间，反刍动物中检测到的血清流行率为 1.6%，范围为 0.4% 至 3.4%。流行率低表明 CCHFV 仅零星传入该国该地区。刚果民主共和国是一个幅员辽阔的国家，这项研究仅在一个省的两个地点进行；因此，调查只能作为进一步流行病学活动的起点。
Crimean-Congo hemorrhagic fever virus (CCHFV) has been detected in many African countries. Unfortunately, little is known about the current CCHFV situation in most of those countries including the Democratic Republic of the Congo (DRC). In over 50 years, three human CCHF cases have been detected in DRC but no seroepidemiological investigation was performed so far. To determine the prevalence of CCHFV-specific antibodies we tested 838 serum samples of cattle, goat and sheep from the southern province Katanga, DRC.The detected seroprevalence in ruminants was 1.6% ranging from 0.4% to 3.4% between the two sampling sites, Kamina and Lubumbashi. The low prevalence indicates only sporadic introduction of CCHFV into this part of the country. DRC is a very large country and the study was performed only at two locations in one province; therefore, the investigations can be only a starting point for further epidemiological activities.