Medical management of deliberate drug overdose: A neglected area for suicide prevention?
Medical management of deliberate drug overdose: A neglected area for suicide prevention?
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DOI：
10.1136/emj.2003.000935
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发表时间：
2004-01-01
影响因子：
3.1
通讯作者：
Murray, V
中科院分区：
文献类型：
--
作者：
Gunnell, D;Ho, D;Murray, V
目的：过量用药占英格兰所有自杀事件的四分之一。有多少人在过量服用药物的直接影响下存活了足够长的时间，以获得医疗照顾，但随后在医院死亡，这是未知的。本研究的目的是确定过量自杀者在医院死亡的比例，并描述其社会人口学特征。方法：对英国常规收集的医院事件统计数据进行横断面分析（1997年至1999年），以确定12岁以上人群中因过量而入院的情况以及这些入院的结果。1997年至1999年期间，有233 756人因用药过量住院，其中1 149人（0.5%）以患者死亡告终，这种死亡占所有用药过量自杀的29%，占自杀总数的7%。从入院到死亡的中位时间为3天（四分位距为1 - 9天）。最常见的药物采取致命过量的扑热息痛化合物，苯二氮卓类，三环/四环抗抑郁药。结论：大约四分之一的所有过量自杀死亡发生后入院。需要进一步进行更详细的研究，以发现对那些服用严重过量药物的人进行更好的入院前和住院医疗管理是否可以防止其中一些死亡。
Objectives: Overdoses account for a quarter of all suicides in England. The number of people who survive the immediate effects of their overdose long enough to reach medical attention, but who subsequently die in hospital is unknown. The aim of this study was to determine the proportion of overdose suicides dying in hospital and describe their sociodemographic characteristics.Method: Cross sectional analysis of routinely collected Hospital Episode Statistics data for England ( 1997 to 1999) to identify hospital admissions for overdose among people aged 12+ and the outcome of these admissions.Results: Between 1997 and 1999 there were 233 756 hospital admissions for overdose, 1149 ( 0.5%) of these ended in the death of the patient such deaths accounted for 29% of all overdose suicides and 7% of total suicides. The median time between admission and death was three days (interquartile range one to nine days). The most commonly identified drugs taken in fatal overdose were paracetamol compounds, benzodiazepines, and tricyclic/tetracyclic antidepressants.Conclusion: Around a quarter of all overdose suicide deaths occur subsequent to hospital admission. Further more detailed research is required to discover if better pre-admission and inhospital medical management of those taking serious overdoses may prevent some of these deaths.