Extra-pulmonary tuberculosis: A retrospective study of patients in Accra, Ghana
Extra-pulmonary tuberculosis: A retrospective study of patients in Accra, Ghana
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DOI：
10.1371/journal.pone.0209650
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发表时间：
2019-01-09
期刊：
影响因子：
3.7
通讯作者：
Klatser, Paul
中科院分区：
文献类型：
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作者：
Ohene, Sally-Ann;Bakker, Mirjam I.;Klatser, Paul
在包括加纳在内的许多非洲国家，关于肺外结核（EPTB）患者的信息有限。本研究的目的是描述从不同类别的卫生设施在阿克拉，加纳肺结核（PTB）患者相比，诊断EPTB患者的流行病学，并确定EPTB patient. Methods之间的死亡率的危险因素，我们进行了回顾性分析，从2010年6月至2013年12月的EPTB和PTB患者从不同类型的卫生设施的医疗记录访问的人口统计学和临床数据。在诊断与EPTB的因素相比，肺结核（PTB）和EPTB患者的治疗结果死亡的相关因素进行了评估，使用Logistic regulation.ResultsOut的3,342个新的结核病患者>= 15年的诊断，728（21.8%）有EPTB的男性：女性的比例为1.17。EPTB的常见受累部位为播散性32.8%、胸膜21%、脊柱13%和中枢神经系统（CNS）11%。EPTB的治疗成功率为70.1%，PTB为84.2%（p
BackgroundInformation on extrapulmonary TB (EPTB) patients is limited in many African countries including Ghana. The study objective was to describe the epidemiology of EPTB patients diagnosed from different categories of health facilities in Accra, Ghana compared to pulmonary TB (PTB) patients and identify risk factors for mortality among EPTB patients.MethodWe conducted retrospective analyses of demographic and clinical data accessed from medical records of EPTB and PTB patients from different types of health facilities from June 2010 to December 2013. Factors at diagnosis associated with EPTB compared to pulmonary TB (PTB) and factors associated with treatment outcome death among EPTB patients were assessed using logistic regression.ResultsOut of 3,342 new TB patients >= 15 years diagnosed, 728 (21.8%) had EPTB with a male: female ratio of 1.17. The EPTB sites commonly affected were disseminated 32.8%, pleura 21%, spine 13%, and Central Nervous System (CNS) 11%. Treatment success rate for EPTB was 70.1% compared to 84.2% for PTB (p